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Showing 1 to 10 of 10 for “"Flotillin"”.
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Molekulare und funktionelle Charakterisierung der reggie/flotillin Gene in Drosophila melanogaster
… zugesprochen. <br> <br>Mit den reggie/flotillin Genen ist ein evolutionär konserviertes paraloges Genpaar identifiziert, dessen Genprodukte in Lipid rafts lokalisiert sind. <br>In der vorliegenden Arbeit wurde die Expression der reggie/flotillin-Gene in Drosophila melanogaster …
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A flotillin-1 és vimentin fehérjék kölcsönhatásának vizsgálata a PP2A Bα fehérjével endotél sejtekben
A flotillin, vimentin, és PP2A B fehérjék kölcsönhatásának vizsgálata, endotél sejtek használatával. Ezen fehérjék tulajdonságait ismertettem. A fehérjéket termeltettük, majd pull down és Western blot kísérletekkel megvizsgáltuk. A kísérletek eredményét részletesen taglaltam, képekkel mellékelve.
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Exosomes act as molecular vehicles contributing to cellular cholesterol efflux
… weiterhin, dass sich die Sekretion von Flotillin-2, einem membranassoziierten Markerprotein für Exosomen, verringert, wenn seine internen Cholesterinerkennungs-/interaktions- Aminosäurekonsensussequenzen (CRAC) mutiert sind. Die Verringerung der Flotillin-2-Expression durch siRNA führt …
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Localisation and expression pattern of the Nogo receptor and its ligand, Nogo-A in cells of the mammalian central nervous system
… located in neuronal lipid rafts by linking it to flotillins, known lipid raft markers. We therefore generated a rabbit polyclonal Nogo receptor antibody from the leucine rich repeat number 9 domain of Nogo receptor polypeptide chain. Together with a commercially available polyclonal antibody …
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Functional characterisation of the lipid raft protein stomatin
… erythrocyte, with defective partitioning of the flotillin proteins into the vesicles. This suggests that stomatin may function as a negative regulator in this vesiculation, possibly due to its interaction with actin and that the flotillins may substitute for stomatin in this process within the …
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The Effect of Endocytosis of Interferon-lambda and The Genotype of IL-10RB on The Cellular Responses to Cytokines
… 이용함을 알 수 있었다. 또한, clathrin, Rho family GTPase와 flotillin 인산화에 의해서는 endocytosis가 조절되지 않음을 밝혔다. IFN-의 자극 에 의해 유도되는 IFN-responsive 유전자 활성은 endocytosis를 저해 하였을 때, 크게 감소함을 보여 endocytosis 억제가 IFN-의기능적인 측면에 영향을 미친다 는 것을 알 수 있었다. IL-10R2 유전자형에 따른 IFN-와 IL-22 반응성 비교 연구에서, 다양한 종류의 사람 간암 세포주에서 …
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Endocytosis mechanism of poly- and lipoplexes in siRNA delivery in HeLa cells
… when polyplexes enter through caveolin-, flotillin- and ARF6-mediated endocytosis pathways. ARF6 might play multiple roles in the delivery and release of the delivered siRNA in cells. Lipoplexes, on the other hand, enter the cells and release siRNA through a method of direct fusion with …
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Functional and molecular characterisation of two stomatin-like proteins from Arabidopsis thaliana
… domain) family (short for Stomatin, Prohibitin, Flotillin HflC/K) of diverse membrane proteins. This protein family is evolutionary conserved with members found in all sequenced eukaryotes and in most prokaryotes. Band-7 family proteins have the ability to oligomerise and generally aid in the …
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The Regulation of Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 2 (SHP-2) in Brain Microglia
… using antibodies directed against p-SHP-2 and flotillin-1 revealed gangliosides-induced clustering and polarization of p-SHP-2 in membrane rafts. Raft-associated regulation of SHP-2 was further demonstrated in fractionation experiments using detergent and detergent-free sucrose gradient …
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Characterizing the Interaction of the ATP Binding Cassette Transporters (G subfamily) with the Intracellular Protein Lipid Environment
… and ACAT1 were observed to co-localize with flotillin-1, a marker of DRMs. We propose that co-localization and complex formation of sterol esterification enzymes and ABC transporters in DRMs reflects a novel mechanism that directs membrane sterols to the esterification reaction. The studies …