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Showing 1 to 9 of 9 for “"Flavoproteins"”.
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Biochemical characterization of respiratory chain flavoproteins
Respiring organisms derive energy mainly from electron transfer reactions that are coupled to the translocation of ions across the cell membrane. This process is performed by a group of membrane-localized protein complexes that hold different cofactors with redox properties, such as flavins, hemes, …
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Photochemistry, photophysics and spectroscopy of redox states of flavins relevant to photoactive flavoproteins
There has been a tremendous interest in the study of flavins and their derivatives in order to gain information valuable for designing model compounds that can mimic the functions of flavoenzymes. This thesis aims a) to explore and enhance the knowledge about the behavior of the flavin cofactors in …
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Amino Acid Sequence Studies on the Beta Subunit of Bacterial Luciferase
… subunit displays no sequence similarity to other flavoproteins, including regions and residues implicated in flavin binding by these enzymes. Therefore, our data do not suggest a role for the (beta) subunit in binding reduced flavin mononucleotide, but they do support the view that luciferase is …
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Targeted depletion of RibF, a putative bifunctional FAD synthetase/ flavokinase in Mycobacterium smegmatis using CRISPR interference
… ribF would disrupt the biosynthesis of all flavoproteins, crippling numerous (essential) processes within the organism. Moreover, based on previous observations in Bacillus subtilis, it was predicted that the mycobacterial ribF homolog might play a role in regulating the rib operon …
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Molecular characterization of three linked genes, fixB, βshbd and adh1 from Clostridium acetobutylicum P262
… caulinodans and the electron transport flavoproteins from humans and rats. Studies on the expression of the three linked genes fixB, βhbd and adh1 were carried out at the transcriptional level. Northern and primer extension analyses indicated that all of the three genes were …
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STRUCTURE-FUNCTION STUDIES OF NOVEL MEDICALLY RELEVANT FLAVOENZYMES
Flavoproteins are involved in a wide range of biological processes, with a variety of catalytic reactions performed, which range from typical redox catalyses such as the dehydrogenation of an amino acid, or activation of dioxygen, to photochemistry; from DNA damage repair to light emission. …
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A bio-optical probe of tryptophyl exposure
Thesis (M.S.)--Michigan State University. Dept. of Biophysics, 1974
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Excited state charge redistribution and dynamics of flavins, flavorproteins, and their cofactors
… experiments of reduced anionic flavins/flavoproteins. The difference dipole moment of the second, more intense, transition was found to be about twice as large as that of the lowest energy transition. With the aid of ab initio calculations, the directions of these dipole moments in the …
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Ultrafast Dynamics of Flavin Cofactor in Photolyase/Cryptochrome Family
<p>Due to the essential role of flavoproteins in light-driven biological activities, such as photoinduced DNA repair and signal transduction, it is of great interest to study the photochemistry and photophysics of flavin cofactor. This dissertation presents a systematic investigation on the …