Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 32 for “"Flatworm"”.
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Flatworm Predation on Juvenile Freshwater Mussels
<p>Free-living flatworms (Phylum Platyhelminthes, Class Turbellaria) are important predators on small aquatic invertebrates. Macrostomum tuba, a predominantly benthic species, feeds on juvenile freshwater mussels in fish hatcheries and mussel culture facilities. Laboratory experiments were …
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Physiology and pharmacology of flatworm muscle
… (VOCCs), in both free-living and parasitic flatworms, has been difficult since the currents carried by these channels are small in amplitude and run down quickly. While the presence of VOCCs in the parasite Schistosoma mansoni has been evident from molecular data, they have escaped …
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The Effect of Caffeine and Ethanol on Flatworm Regeneration.
<p>Flatworms, or planarian, have a high potential for regeneration and have been used as a model to investigate regeneration and stem cell biology for over a century. Chemicals, temperature, and seasonal factors can influence planarian regeneration. Caffeine and ethanol are two widely used drugs …
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Carbon dioxide fixation and glycogenesis in the flatworm Hymenolepis diminuta
The cyclophyllidean cestode Hymenolepis diminuta has been found to incorporate C1402 into organic acids, amino acids, and glycogen upon in vivo incubation. This incorporation was sensitive to incubation conditions, more C1402 being incorporated aerobically than anaerobically, and was also …
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Reaction of the marine flatworm Macrostomum lignano exposed to xenobiotics
… a prominent role in this context. The marine flatworm Macrostomum lignano is a perfect model organism for this purpose. A key mechanism of xenobiotic-induced toxicity is the formation of reactive oxygen species, which can result in cell death. This was observed in the Macrostomum model. ROS …
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Bioinspired Structural Revision of the Marine Flatworm-Derived Alkaloid Pseudocerosine
… Isolated as a deep blue pigment from the marine flatworm Pseudoceros indicus, this natural product was reported to contain a unique heteroaromatic scaffold comprising an azafulvene-embedded azepinoindole and an acetamidyl aminal moiety.....
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Mechanisms Controlling Hatching of Winter Eggs of the Flatworm Mesostoma Ehrenbergii
Flatworms are the simplest of the triploblastic, bilaterally symmetrical protos tomes. As a group , they are worm-shaped with the body usually dorso-ventrally flattened. The epidermis is ciliated. | Most members of the class Turbellaria are free- living. Although planarians have frequently been …
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Functional Studies of Stem Cells in the Parasitic Flatworm Schistosoma mansoni
Schistosomes are parasitic flatworms that infect over 200 million people, primarily in poverty-stricken developing countries, causing extensive morbidity and mortality. Schistosomes have a great deal in common with other parasitic flatworms such as liver flukes and tapeworms. Namely, they are …
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Use of praziquantel for treatment of flatworm parasites in centrarchid fish
… TREMATODES. PRAZIQUANTEL IS A DRUG WITH ANTI-FLATWORM ACTIVITY AND IS WIDELY USED IN HUMAN AND VETERINARY MEDICINE. AT THIS TIME PRAZIQUANTEL IS NOT APPROVED FOR THE USE IN FISH, BUT USE MAY BE JUSTIFIED UNDER THE GUIDANCE OF THE ANIMAL MEDICINAL DRUG USE CLARIFICATION ACT (AMDUCA). WHILE SOME …
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Investigating Adult Stem Cell Lineage Specification in the Freshwater Flatworm Schmidtea mediterranea
Adult stem cells (ASCs) serve to facilitate tissue turnover during the lifespan of an organism. The goal of my research has been to deepen our understanding of how ASCs become specified towards differentiation to produce physiologically functional cell types. To this end, I have chosen to use the …
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Mobile genetic element contribution to the genome architecture of the human parasitic flatworm Schistosoma mansoni
Schistosomiasis is a parasitic disease that affects approximately 250 million individuals worldwide, resulting in an estimated loss of more than 20 million disability-adjusted life years. Around 700 million people, predominantly in developing countries, live in at-risk areas. Schistosomiasis is …
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STK25 and TAO Regulate Muscle-Specific Transcription and Muscle Function in the Parasitic Flatworm Schistosoma Mansoni
Schistosomiasis, a disease caused by parasitic flatworms called schistosomes, affects 240 million people in developing regions, including large parts of Africa, Asia, and South America. In some of these areas, the disease affects over 50% of the population, making Schistosomiasis second only to …
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Planaria as a model for the effects of the co-use of alcohol and nicotine
… drug versus the combined drugs in the planarian flatworm. Planarian locomotor velocity (pLMV) and atypical behaviours are the behavioural paradigms used in this experiment to quantify the withdrawal effects observed. Results reveal a complex relationship between alcohol and nicotine with …
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Understanding the role of Stylochus ellipticus as a predator of Crassostrea virginica in Chesapeake Bay tributaries
… in Chesapeake Bay. Here, I examine the polyclad flatworm Stylochus ellipticus and its potential role as an important predator of C. virginica. Using small-fragment size C. virginica specific DNA primers, oyster DNA was successfully detected in whole organisms homogenates of wild-caught S. …
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Engagement of human host receptors by the antiparasitic drug praziquantel
… of which may provide clues to homologs in flatworms. Here, in Chapter 2, I show that PZQ engages human 5-HT2B receptors in vivo, ex vivo on isolated vessels and in vitro by a variety of approaches. PZQ engagement of 5-HT2B R on vascular smooth muscle cells caused vasoconstriction in …
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Liquid chromatography-mass spectrometry-based neuropeptide characterizations across neuronal models
… have been explored. For example, the flatworm (Schmidtea mediterranea) provides understanding of regeneration and reproduction, while the comb jelly (Pleurobrachia pileus), as the earliest branching in extant animals, is an excellent model for investigating animal evolution. The …
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Postembryonic Polarity Modification in the Acoel Convolutriloba longifissura
… regeneration and asexual reproduction, the acoel flatworm <em>Convolutriloba longifissura</em> is unusual in its ability to modify left-right (L-R) axis polarity during longitudinal fission. We have developed <em>C. longifissura</em> as a model for studying the mechanisms of L-R polarity …
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Schmidtea mediterranea planaris as a novel animal model for investigating the dynamics of nervous system development in fetal alcohol spectrum disorder
… In this thesis, we propose that the freshwater flatworm planarian species, Schmidtea mediterranea, has the capability to fulfill this need. Planaria have the ability to completely regenerate fragments into intact, functional animals, and in these studies, we exploited this property to …
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An insulin-like peptide regulates size and adult stem cells in planarians
… manner. For example, the regenerating flatworm Schmidtea mediterranea becomes smaller, or degrows, during periods of starvation. These animals provide an opportunity to readily observe adult stem cell population dynamics in response to nutritional cues. We explore the role of insulin …
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Liver fluke development: a target for parasite control?
Fasciolosis, a debilitating disease caused by flatworm parasites belonging to the genus Fasciola, is a prominent threat to global food security due to its widespread infection of agriculturally significant ruminants. Recent studies have identified a population of proliferative cells within Fasciola …
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