Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 72 for “"Flagellum"”.
-
Flagellum assembly in protozoan parasites
… and division. Our findings show that the new flagellum does not rotate around the old flagellum and cytokinesis creates a membrane indentation that is retained in daughter cells until early in the next cell cycle. Transition fibres serve as docking sites for axonemal proteins, ensuring proper …
-
Counterbending in a flagellum macromodel
The flagellum is one of the most critical biological compenents in nature; it is a basic feature common to many different types of cells and allows for even the most primitive cells to move around. However, the structure of the flagellum is far from simple. The inner core consists of a 9+2 …
-
Investigation of conserved Flagellum proteins in Trypanosoma brucei
… eukaryotic cilia and flagella as it has a single flagellum that remains assembled throughout the cell cycle. The new flagellum assembles in a known position relative to the old flagellum, therefore creating a model system of identifiable organelle generations. In additional to a sequenced genome, …
-
Identification of the Polar Flagellum Genes in Azospirillum brasilense
… a mixed pattern of flagellation: a single polar flagellum for motility in liquid medium and lateral flagella which might be involved in motility across the root surface and or attachment to the root hairs of plants. Flagella dictate <em>A. brasilense</em> chemotactic ability and motility, which …
-
The role of the flagellum attachment zone in Leishmania mexicana flagellar pocket architecture
… shown that a large cytoskeletal structure, the flagellum attachment zone (FAZ), which connects the flagellum to the cell body, was an important contributor to the maintenance of the flagellar pocket architecture and its function. However, a poor understanding of FAZ molecular organisation and …
-
The role of intraflagellar transport during the disassembly of the Leishmania mexicana flagellum
… of the Leishmania parasites to remodel its flagellum is important for its survival as it navigates through multiple host environments during its lifecycle. The most striking remodelling step is during the differentiation from the long, motile flagellum of promastigotes to the short, sensory …
-
Probing the assembly of the <em>Bacillus subtilis</em> flagellum and its role in signal transduction.
… further evidence that the <em>B. subtilis</em> flagellum is regulated by both conserved and species-specific means. These experiments led to YvyG being re-named as FlgN. Despite previous work suggesting that phosphorylation of YvyG was important for protein function and localisation, the data …
-
Understanding the composition and function of the flagellar groove in bloodstream form Trypanosoma brucei
… of the bloodstream from of T. brucei is the flagellum, which is laterally attached to the side of the cell body and is not disassembled during the cell cycle. Instead, a new flagellum is formed alongside the old flagellum, with the distal tip of the new flagellum embedded within a cell body …
-
The role of transition fibre proteins in regulating CEP164C assembly and localisation to the flagellum in the African Sleeping Sickness parasite Trypanosoma brucei
… fibres of the basal bodies, essential for flagellum assembly and cell division in the procyclic cycle.. In particular, CEP164C is thought to be a key organiser of the transition fibres and an integral part of the “Grow and lock model”, which prevents the old flagellum from growing and …
-
Predator Behavior and Prey Demography in Patchy Habitats
… ecology and spatial ecology of Masticophis flagellum (Coachwhip) using capture-mark-recapture and radio telemetry techniques. I also examined the influence of saurophagous snake abundance on the survival rate of Sceloporus woodi (Florida Scrub Lizard) populations. Masticophis flagellum …
-
Functional genomics of motile commensal intestinal bacteria
… have significant immunomodulatory potential. The flagellum-biogenesis genotype and phenotype of Lactobacillus ruminis, an autochthonous intestinal commensal, was studied. The flagellum-biogenesis genotypes of motile enteric Eubacterium and Roseburia species were also investigated. Flagellin …
-
The interplay between pathogenic bacteria and bacteriophage Chi: New directions in motility and phage-host interactions in Enterobacterales
The bacterial flagellum is a rotary motor that propels motile bacteria through their surroundings via swimming motility, or on surfaces via swarming motility. The flagellum is a key virulence factor for motile pathogenic bacteria. Viruses that infect bacteria via this appendage are known as …
-
Antigenic and functional differences between the polar and lateral flagella of Azospirillum brasilense
… of the genus Azospirillum possess a single polar flagellum when grown in broth; when grown on solid media they also possess numerous lateral flagella of shorter wavelength (0.7 µm vs. 1.2 µm) and thinner diameter (13.5 nm vs. 18 nm). The antigenic and functional differences between these two types …
-
Unravelling the molecular mechanisms of Leishmania mexicana adhesion in the sand fly vector
… efficient transmission and occurs through its flagellum via a complex adhesion plaque from which filaments in the modified flagellum extend towards the cell body and likely connect to the flagellum attachment zone (FAZ), a cytoskeletal structure important for cell morphogenesis. While three …
-
Substrate targeting and recognition in the flagellar type III secretion pathway
The bacterial flagellum is a complex molecular machine that enables bacteria to move as well as having additional roles in biofilm formation, adhesion and host cell invasion. The sequential assembly of the flagellar rod, hook and filament requires the export of thousands of structural subunits …
-
Molecular, biochemical and functional analysis of kinesins in Leishmania mexicana
… of three kinesins thought to be associated with flagellum formation. Initially the cloning, mapping, and expression of the novel kinesin LmxKin29 were achieved. LmxKin29 is expressed in both the amastigote and promastigote life stages of L. mexicana. LmxKin29 can be assigned to the “orphan” …
-
INVESTIGATION OF THE DISTAL APPENDAGE PROTEIN CEP164 IN Trypanosoma brucei
… Understanding of basal body docking and flagellum length regulation in the Trypanosoma brucei cell is limited and is thought to involve the transitional fibres and surrounding structures. Three diverse Cep164 orthologues in the T. brucei parasite have been identified, but knowledge on …
-
Molecular characterization of motility genes in Bacillus subtilis
The synthesis of the bacterial flagellum is a complex process requiring up to fifty gene products in organisms such as Escherichia coli and Bacillus subtilis. Several genes involved in the process of flagellar synthesis have been identified and characterized from the che/fla operon of B. subtilis, …
-
Theoretical and computational investigations into structure-function relationships of biomolecular machines at atomic resolution
… The last project is a study of the growth of flagellum, which is an hours-long process. The building blocks of flagella, flagellin monomers, are pumped by a type III secretion system, through the flagellar interior channel to the growing tip. After a flagellin monomer binds to the tip of the …
-
Identification of TbRP2-interacting proteins using proximity-dependent biotinylation (BioID)
… brucei, a tractable model to study eukaryotic flagellum assembly but also a parasite of medical and veterinary importance in subSaharan Africa. Thus, the study of RP2 in trypanosomes has relevance for parasitology, but also the human inherited disease retinitis pigmentosa. However, important …
Page 1 of 4