Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Fibrotic scar"”.
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The Influence of SPARC on Collagen Deposition in Asbestos-Induced Pulmonary Fibrosis
… involves the invasion of lung tissue with fibrotic, scar tissue and affects roughly five million people total worldwide. Fibrotic development in the lung has several causes, including chronic inflammatory diseases, infections, medical compounds, and environmental agents. There is no known …
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The Influence of SPARC on Collagen Deposition in Asbestos-Induced Pulmonary Fibrosis
… involves the invasion of lung tissue with fibrotic, scar tissue and affects roughly five million people total worldwide. Fibrotic development in the lung has several causes, including chronic inflammatory diseases, infections, medical compounds, and environmental agents. There is no known …
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Correlation of signal-averaged electrocardiogram and late gadolinium enhancement cardiovascular magnetic resonance in the detection of myocardial fibrosis in arrhythmogenic right ventricular cardiomyopathy and other myocardial disorders
Background. The diagnosis of fibrotic scar tissue in arrhythmogenic right ventricular cardiomyopathy (ARVC) and other cardiomyopathies is crucial as it forms the substrate for ventricular tachycardia (VT) and fibrillation (VT). Signal-averaged electrocardiography (SAECG) abnormalities are frequent …
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Architectural, mechanical and biochemical control of collagen films and scaffolds to guide neural- and fibroblast cell behaviour
… competition between neural cell attachment and fibrotic scar tissue formation also needs to be addressed. The goal of this thesis was to investigate the effects of mechanically and biochemically tailored collagen scaffolds on the attachment, migration and proliferation of neural- and fibroblast …
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Role of extracellular environment in mechanical properties of human cardiac fibroblasts and myofibroblasts
… heart failure. Collectively, the formation of fibrotic scar tissue in the left ventricle inhibits its contractile function and leads to a cardiac output loss. Cardiac fibroblast and myofibroblast cells are integral in the remodelling of injured tissue and are the most anticipated therapeutic …
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Control of Cardiac Remodelling during Ageing and Disease by Epigenetic Modifications and Modifiers
… increases, replacing healthy myocardium with fibrotic scar tissue. Together, CM hypertrophy and fibroblast hyperplasia progressively reduces cardiac function and the ability of the heart to adapt to environmental stressors or damage. Under continued stress or through natural ageing, the heart …
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Meningeal Fibrosis in the Axolotl Spinal Cord: Extracellular Matrix and Cellular Responses
… regard to the deposition and remodeling of the fibrotic ECM, which is found to be similar in composition to hydrogel scaffolds being studied in mammalian SCI. It is shown that meningeal fibroblasts are the primary source of the extensive fibrillar collagen deposition that fills the entire spinal …