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Showing 1 to 4 of 4 for “"Fexofenadine"”.

  1. FEXOFENADINE AND ORGANIC ANION TRANSPORTING POLYPEPTIDES (OATPs): TRANSPORT AND DRUG-DRUG INTERACTIONS

    … major role in the absorption and disposition of fexofenadine, suggesting this drug could be used as a probe of transporter activity. When fexofenadine was administered in combination with four drugs (buspirone, caffeine, dextromethorphan and losartan) used to probe cytochrome P450 (CYP) …

    ku Repository record for FEXOFENADINE AND ORGANIC ANION TRANSPORTING POLYPEPTIDES (OATPs): TRANSPORT AND DRUG-DRUG INTERACTIONS (opens in a new tab)

  2. Age-Associated Expression Patterns of OATP 1B1 and OATP 1B3 and Their Effect on the Disposition of Fexofenadine

    … than 65% homology to the human members. Using fexofenadine as a probe for Oatp1b2 activity, it was found that Oatp1b2-/- mice had 2.1 fold higher exposure as compared to the wild-type mice. The Oatp1b2-/- also had 55% of the fexofenadine clearance and 63% the volume of distribution as compared …

    tenn-hsc Repository record for Age-Associated Expression Patterns of OATP 1B1 and OATP 1B3 and Their Effect on the Disposition of Fexofenadine (opens in a new tab)

  3. Racial differences in cardiovascular responses following an acute bout of aerobic exercise

    … take either a combined H1R and H2R antagonist (fexofenadine and ranitidine) or a control placebo followed by the other condition on the second visit between 3 pm to 8 pm. During study visits, subjects rested in the supine position for baseline BP, cardiac output, peripheral resistance and …

    uiuc Repository record for Racial differences in cardiovascular responses following an acute bout of aerobic exercise (opens in a new tab)

  4. Investigating the role of nonantibiotic chemical contaminants in the evolution of antibiotic resistance

    … that many chemical contaminants, such as fexofenadine, and prometon, had low removal efficiencies. This study suggests the prevalence of chemical contaminants and their coexistence in the wastewater. I then investigated the effects of pesticide mixture, which are nonantibiotic chemical …

    uiuc Repository record for Investigating the role of nonantibiotic chemical contaminants in the evolution of antibiotic resistance (opens in a new tab)