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Showing 1 to 1 of 1 for “"Ferroportin-1 (FPN1)"”.

  1. Restored iron transport by a small molecule promotes absorption and hemoglobinization: discovery, development, and mechanistic studies

    … of iron out of J774 macrophages deficient in ferroportin. The same compound promotes gut iron absorption in DMT1-deficient rats and ferroportin-deficient mice, as well as hemoglobinization in DMT1- and mitoferrin-deficient zebrafish. These findings illuminate a general mechanistic framework …

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