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Showing 1 to 6 of 6 for “"Ferrochelatase"”.

  1. Die genetische Basis der erythropoetischen Protoporphyrie in Deutschland : molekularbiologische Untersuchungen im Ferrochelatase-Gen

    Gutierrez, Pamela Poblete-2006

    aachen Repository record

  2. Investigation of an atypical protoporphyric family in South Africa

    Haumann, Carel EduardDivision of Anatomical Pathology2010

    … and an absence of mutations in the ferrochelatase gene or haplotype markers associated with erythropoietic protoporphyria. We have reviewed clinical data from this family, established a ferrochelatase enzyme assay in our laboratory, and shown normal ferrochelatase enzyme activity in …

    cape-town Repository record

  3. Designing Novel Blue Copper and Purple CuA Centers in Azurin With Natural and Unnatural Amino Acids

    Berry, Steven MarkUniversity of Illinois at Urbana-Champaign2015

    … a 2Fe-2S cluster binding loop from human ferrochelatase into azurin. Preliminary iron binding studies indicate the assembly of a 4Fe-4S or a 2Fe-2S iron sulfur cluster.

    uiuc Repository record

  4. The molecular mechanism of action of the antiangiogenic natural product, cremastranone

    Basavarajappa, Halesha Dhurvigere2016

    … a chemical proteomic approach. I identified ferrochelatase (FECH) as a specific interacting protein partner of cremastranone using photoaffinity chromatography. Hence, I hypothesized that cremastranone exerts its antiangiogenic activities through modulation of the functions of FECH. …

    iupui Repository record

  5. Characterization of the Hepatotoxicity of Rifampicin and Isoniazid

    Brewer, Christopher T.2021

    … to cholestasis fol owed by liver injury. Both ferrochelatase (<em>FECH</em>/<em>Fech</em>) and aminolevulinic acid synthase 1 (<em>ALAS1</em>/<em>Alas1</em>) are crucial enzymes in regulating heme biosynthesis. Isoniazid has recently been reported to up-regulate <em>Alas1 </em>but down-regulate …

    tenn-hsc Repository record

  6. Isothermal Titration Calorimetry Studies Of Protein-Mediated Interactions And Preliminary Structural Studies Of Tandem Pdz1-2 Domain Of Psd-95 Protein

    Jankovic, Ana2010

    … delivers mitochondrial Fe(II) to the enzymes ferrochelatase and the ISU apparatus for completion of heme and Fe-S cluster biosynthesis. Monomeric frataxin protein has a high affinity for ferrous ion, completely saturating at 2:1 iron to protein ratio. The micromolar dissociation constants …

    wayne-thes Repository record