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Showing 1 to 2 of 2 for “"Ferritinophagy"”.

  1. Determining the Molecular Underpinnings of Iron Homeostasis in Human Cells

    … the protein interactions involved in ferritinophagy, a form of selective autophagy that leads to the lysosomal degradation of ferritin. Extending prior work that identified key components supporting ferritinophagy, including the selective autophagy receptor protein NCOA4 and its …

    mit Repository record for Determining the Molecular Underpinnings of Iron Homeostasis in Human Cells (opens in a new tab)

  2. V-ATPase regulation of Hypoxia Inducible transcription Factors

    Metazoans have evolved conserved mechanisms to promote cell survival under low oxygen tensions by initiating a transcriptional cascade centered on the action of Hypoxia Inducible transcription Factors (HIFs). In aerobic conditions, HIFs are inactivated by ubiquitin-proteasome-mediated degradation …

    cambridge Repository record for V-ATPase regulation of Hypoxia Inducible transcription Factors (opens in a new tab)