Global ETD Search
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Showing 1 to 14 of 14 for “"Fenland"”.
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Nature-based recreation and leisure in fenland rural ecomies - A case study approach.
… as factors of economic generators within rural, fenland landscapes, and thus as contributors to rural economies. Using a case study approach, the research investigated the Humberhead Levels as a region of potential nature-based recreation and leisure demand, informed by existing, similar demand …
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Understanding Temporal Movement Behaviour Patterns: Measurement, Epidemiology, and Cardiometabolic Health Implications
… of UK adults using wearable data from the Fenland Study; (3) investigate cross-sectional and longitudinal associations between movement behaviour complexity and the risk of cardiometabolic disease. The first part of my research involved a systematic review which identified and compared …
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Eating behaviour and the aetiology of obesity
… using a genetic risk score (GRS) approach in the Fenland study (n=9667). The BMI-GRS primarily influenced fat mass, confirming its utility in modelling the effects of adiposity and BMI, as well as in exploring the mechanisms of genetic predisposition to obesity. Emotional eating (EE), uncontrolled …
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The descriptive and aetiological epidemiology of physical activity: composition, volume, and intensity.
… and Nutrition Survey, the Cambridgeshire-based Fenland Study, and the Russian-based Know Your Heart Study, along with an ecological analysis of 35 population estimates of physical activity energy expenditure from populations as diverse as Arctic Inuit to the Maasai of Kenya. In summary, the …
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The ecology of the zander, Stizostedion lucioperca L.
… of the methods used to obtain zander fom Fenland and Midland zander habitats during the period 1978 to 1981. The growth characteristics of the major zander populations were validated. The feeding habits of the zander were determined from species, size and number of prey eaten: comparisons …
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Inclusive and adaptive assessment of cardiorespiratory fitness for population health research
… disease, type 2 diabetes, and cancer. In the Fenland study, I validate and apply a ramped treadmill test for estimating fitness in approximately 10,000 adults, revealing the importance of physical activity and body size on population variation in fitness. I validate the use of heart rate …
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Dairy products and cardio-metabolic health: aspects from nutritional, molecular and genetic epidemiology
… or elderly people. Using data from the large Fenland (n~12,000) and EPIC Norfolk (n~25,000) studies, I investigated associations of total and types of dairy consumption with markers of metabolic risk and adiposity as potential pathways to cardio-metabolic disease. The analyses showed …
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Dendrochronological investigations of living and relict yew trees from eastern England
… from near sea-level peat-rich sediments in the Fenland region of eastern England. Using dendrochronological and radiocarbon dating, I develop two floating TRW chronologies for the mid-Holocene. Stable oxygen (δ18O) isotopes are then used for establishing an absolute date via cross-dating against …
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A Population Perspective on Physical Activity and Health
… the third study using a large cohort study (the Fenland Study) with detailed characterisation of diet and physical activity (including objective measurement) describes the baseline associations between active commuting and objective measures of adiposity. The second part of my thesis describes …
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Investigation of Genetic and Behavioural Determinants of Type 2 diabetes and Glycaemic Traits
… genetic risk scores for glycaemic traits in the Fenland study. I did not find any significant interaction. Alternatively, using an agnostic approach, I searched for potential interactions with PAEE across the genome. Preliminary analyses detected three variants showing genome-wide significant …
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Combined associations of diet quality, physical activity, and their changes over time with cardiometabolic risk and mortality
… risk factors were assessed, using data from the Fenland Study among 7,256 participants. For markers of adiposity, I used data on changes in weight and body mass index as well as changes in body composition (body fat distribution), assessed using dual-energy X-ray absorptiometry and abdominal …
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Using human genomics to decipher biological mechanisms underlying reproductive ageing and fertility in women
… of 10,713 European ancestry individuals in the Fenland study. Although this analysis did not identify robust protein candidates associated with ANM, it demonstrates the potential of such approaches to discover new biomarkers. Chapter 6 presents the largest genomic meta-analysis for age at …
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Investigating the Relationship between Markers of Ageing and Cardiometabolic Disease
Human ageing is accompanied by characteristic metabolic and endocrine changes, including altered hormone profiles, insulin resistance and deterioration of skeletal muscle. Obesity and diabetes may themselves drive an accelerated ageing phenotype. Untangling the causal web between ageing, obesity …
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Improvement and environmental conflict in the northern fens, 1560-1665
This thesis examines ‘improvement’ of wetland commons in early modern England as a contested process of rapid environmental change. As a flagship project of agrarian improvement, drainage sought to alchemise pastoral fen commons into arable enclosed terra firma and promised manifold benefits for …