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Showing 1 to 3 of 3 for “"Fenbufen"”.
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Synthesis and characterisation of new multi-component compounds containing the non-steroidal anti-inflammatory drugs fenbufen and S(+)-ibuprofen
Fenbufen and S-(+)-ibuprofen are non-steroidal anti-inflammatory drugs with poor aqueous solubility. In attempts to improve their solubility and bioavailability, crystal engineering techniques were employed to synthesise salts, co-crystals and cyclodextrin inclusion complexes containing these …
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Co-crystal screening of poorly water-soluble active pharmaceutical ingredients. Application of hot stage microscopy on curcumin-nicotinamide system and construction of ternary phase diagram of fenbufen-nicotinamide-water co-crystal system.
… system. In order to acquire related techniques, fenbufen, a poorly water soluble drug, was selected. The result showed the huge difference in solubility between fenbufen and nicotinamide lead to difficulty in the construction of phase diagram.
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Identification of Novel Acid-Sensing Ion Channel 3 Modulators using in silico Modelling and Screening
… these criteria, three molecules (diflunisal, fenbufen and tolmetin) were chosen from a number of hits and were then tested for their ability to modulate the function of rASIC3 transiently transfected in Chinese hamster ovary cells using whole-cell patch-clamp electrophysiology. This *in …