Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Fecal microbiota transplantation"”.
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Reevaluating fecal microbiota transplantation for recurrent clostridium difficile infection
… relapsing after antibiotic treatment for CDI. Fecal Microbiota Transplantation (FMT) has emerged as a novel therapy for recurrent CDI, but the majority of the literature to date is made up of uncontrolled case series, so FMT’s true efficacy compared with standard antibiotic regimens remains …
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Computational insights into the ecology of the human microbiota
… microbes that inhabit the human body, the human microbiota, is important to human health and disease. These microbes contribute to human metabolism, the development of the immune system and pathogen resistance, while imbalances among them have been associated with several diseases. In this work, …
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Gut microbes and serum metabolomics in canine with diabetes mellitus
… unbalanced gastrointestinal (GI) microbiome with fecal microbiota transplantation (FMT) may help improve gut function and glycemic control of diabetic dogs. The results presented herein are part of a larger prospective randomized, place-controlled, double blinded clinical study that evaluated the …
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The gut microbiome: A key regulator of mucosal tolerance, barrier function, and vaccine response
… Through coevolution with the intestinal microbiota, mammals have developed a highly specialized mucosa that not only facilitates digestion and nutrient absorption but also maintains a balanced relationship with symbiotic and mutualistic microorganisms and as well as commensals while …
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Using Culturomics to Characterize the Gastrointestinal Microbiota of Donors for Patients with Bipolar Disorder Experiencing Depression
… axis, which can influence mood and behaviour. Fecal microbiota transplantation (FMT) has been shown to alter the gut bacterial composition of recipients. In a phase 2/3 double-blinded randomized controlled trial (RCT) completed in 2022, participants diagnosed with BD were randomized 1:1 to …
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Modulating the gut microbiome to improve immune checkpoint inhibitor response to cancer: current therapies and emerging methods
… be manipulated through many methods, including fecal microbiota transplantation (FMT), transferring bacterial isolates or consortia, probiotics, antibiotics, and soluble dietary fiber. For clinical insights, it is important to consider how the pre-treatment microbiome of patients may affect …
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Understanding community changes in ecological systems: a probabilistic and geometric perspective
… infecting humans) or human actions (e.g., fecal microbiota transplantation). Although previous studies have theoretically explored criteria for successful coexistence, invasion, and assembly under specific or fixed environmental conditions, the variable and often unknown environmental …
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The Gut Microbiome as a Novel Approach for Reversing Long-Term Inflammation and Accelerated Aging Across the Lifespan
… sequencing was used for bacterial analysis of fecal samples and validating successful fecal microbiota transplantation (FMT). Mass spectrometry metabolomics measured alterations in tryptophan pathways.</p> <p><strong>Results</strong>: Aged mice displayed a distinct peripheral immune cell …
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Differential progression of pancreatic premalignancy in geographically distant murine transgenic cohorts uncovers key role of microbial metabolites
… shown to influence the host immune system. The microbiota, or the community of microbes, present in the gut has gained recent attention for the pivotal role it plays in myriad aspects of host physiology. The relationship between microbes and cancer is complex. Recent studies have shown that PDAC …