Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 80 for “"Fear Conditioning"”.
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Ontogeny of contextual fear conditioning: behavioral, neuropharmacological and molecular mechanisms
… developing rodents using a variant of contextual fear conditioning called the context preexposure facilitation effect (CPFE). The CPFE is a variant of contextual fear conditioning in which acquisition of the contextual representation (preexposure phase) and association of the retrieved contextual …
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Antidepressant-Like Effects of Ketamine on Fear Conditioning and Extinction
… emotional events can be studied in animals using fear conditioning and extinction paradigms. Fear conditioning trains an animal to associate a neutral cue with an emotionally aversive experience, while extinction learning challenges this association by forming a new memory that identifies the cue …
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Fear Conditioning as an Intermediate Phenotype: An RDoC Inspired Methodological Analysis
… novel experimental and statistical approaches. Fear learning paradigms represent a promising methodology for elucidating connections between acute threat (“fear”) circuitry and fear-related clinical difficulties. However, traditional analytical approaches rely on central tendency statistics, …
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The social transmission of associative fear in rats : mechanisms and applications of fear conditioning by proxy
… the robust production of responses makes direct fear conditioning the most frequently used paradigm in the research of fear and anxiety disorders. Fear can also be acquired from a social context, such as through observing the fear expression of a conspecific (Mineka et al., 1984, Mineka and Cook, …
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Strain-dependent and age-dependent effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning.
… from chronic nicotine administration on fear conditioning in 8 strains of inbred mice. Furthermore, nicotine withdrawal-related changes in somatic signs and the elevated plus maze were examined because nicotine withdrawal consists of multiple symptoms that can include increased somatic …
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Tone-evoked Fos labeling in the central auditory pathway : effects of stimulus intensity and auditory fear conditioning
… to study how learning, in particular auditory fear conditioning, changes the pattern of neuronal activation of neurons, as measured with Fos labeling, in the central nervous system. Conditioning led to an increase in Fos labeling in central auditory nuclei.
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The effects of chronic intermittent ethanol exposure on fear conditioning in rats: an investigation of the comorbidity of PTSD and AUD
… ethanol (CIE), a model of alcohol dependence, on fear conditioning, a model of fear learning that engages circuits that are dysregulated in PTSD, in male Long Evans rats. We further expanded this research by looking at the effects of this exposure on subsequent ethanol drinking behaviors, using a …
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Birdie see, Birdie do: Zebra finch observational learning in three cognitive domains with discussion of cerebellar involvement
… learning (stimulus enhancement, observational conditioning, and imitation). I found that female zebra finches selected males based on observations of the traits of the females paired with the males but not based on observation of simply whether the male was associated with a female. Zebra …
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Common and Distinct Neural Mechanisms of Fear Acquisition and Reversal in comorbid Autism with Social Anxiety and Social Anxiety Disorder uncomplicated by Autism
… exist in neural and biological mechanisms of fear conditioning. Characterization of whether neural mechanisms of fear are different within ASD with comorbid SAD and SAD alone may better inform clinical treatments. Accordingly, the present study characterizes neural responses during a …
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NICOTINE MODULATION OF THYROID HORMONE SIGNALING AND ITS CONTRIBUTION TO COGNITION
… hippocampus-dependent memory using a contextual fear conditioning paradigm. It was hypothesized that TRs would be critical for the acute effects of nicotine on contextual fear conditioning. Mice lacking the TRβ and TRα1 gene (KOs) and wildtype littermates (WTs) were administered acute nicotine …
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Protein SUMOylation is a Sex-Specific Regulator of Fear Memory Formation in the Amygdala
… of protein ubiquitination in the formation of fear-based memories, few studies have been conducted examining the role that SUMOylation plays in this same process. The amygdala is the main site of storage for emotional memories and there is strong evidence that protein ubiquitination is critical …
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Exploring the role of Rapgef6 in neuropsychiatric disorders
… behavioral domain as measured by reduced fear conditioning and anxiolysis. More disseminated behavioral functions such as startle and prepulse inhibition were also reduced, while locomotion was increased. Hippocampal-dependent spatial memory was intact, as was prefrontal cortex function on …
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Dating Anxiety and Paternal Dating Rules
… including parental anxiety, overcontrol, and fear-conditioning. In regard to dating, fathers have been shown to be more controlling and restrictive than mothers in their rule use. The present study aimed to examine the relation between adolescents' experience of dating anxiety and paternal …
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Partial reinforcement effects in Pavlovian (CER) conditioning: between and within subjects
… CS. The results were discussed in terms of a fear conditioning model and a predictability model.
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Stress and Hippocampal Plasticity
… memory process is dissected using a contextual fear conditioning paradigm in order to identify the component that can affect hippocampal cell proliferation. The results presented demonstrate that repeated stress, which activates the hypothalamic-pituitary-adrenal (HPA) axis and leads to …
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Impact of Oxytocin and Tetrahydrocannabinol on signs of fear in the rat
… of intranasal OXT attenuates signs of fear in rats; however, the impact of intraperitoneal (i.p) OXT pre-treatment on signs of fear in rats is unknown. We also explored the effects of delta-9 (psychoactive component of cannabidiol) and delta-8 (delta-9 isomer) THC pre-treatment on …
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Pharmacological Intervention Reduces Hippocampal Hyperactivity in a Mouse Model of Psychosis
… oral), as well as cued and contextual fear conditioning with haloperidol (1.75mg/kg/day oral). Haloperidol, but not levetiracetam, rescued the deficit in Social Recognition Memory. However, haloperidol did not alter the increased freezing in fear conditioning paradigm. Finally, in …
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THE EFFECT OF ENGAGEMENT IN COGNITIVE REAPPRAISAL IN RESPONSE TO PREVIOUSLY CONDITIONED STIMULI ON ONLINE AND LONG-TERM EXPECTANCY RATINGS AND EMOTION INDICES
… underwent habituation and simple discriminatory fear conditioning. Stimuli were pictures of a snake and a spider. Two days later participants returned to the laboratory and were either i) cued to engage in cognitive reappraisal while imagining the stimuli ii) exposed to the stimuli with no …
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The Mechanisms Underlying Olfactory Vicarious Fear Learning in Rats
… how male rats observed and internalised the fear behaviour of other male rats. A robust olfactory fear conditioning protocol was set up, in which an otherwise neutral odour, acetophenone, was paired with foot shocks. The rats subsequently displayed freezing behaviour. In order to assess the …
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