Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Fatty acids (FAs)"”.
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Investigating the host-microbe dialogue in aging
… host produced but bacterially modified Bile acids (BAs) and on dietary microbially derived Fatty acids (FAs) as key elements to indicate gut microbial potential impactful roles. In the context of Chapter 3, this thesis examined the levels of BAs and FAs, to identify convergence on specific …
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Application Of Method Developed For The Identification And Quantification Of Polar Components In Organic Liquid Products Of Selected Crop Oils And Deciphering The Mechanistic Aspects Of Cracking
… by the pyrolysis of crop oils. Presence of fatty acids (FAs) will limit the applicability of plant oils as biofuels since they are corrosive and form wax-like crystals at a cloud point that would plug filters. However, short chain FAs have a high commercial value as byproducts of biofuel …
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Temporal Fatty Acid Fluctuations of Pachygrapsus crassipes in Southern California
<p>The current investigation identified fatty acids (FAs) and quantified total and specific FA concentrations in the striped shore crab, <em>Pachygrapsus crassipes.</em> I examined changes in the abundance of individual FAs and FA saturation categories (saturated, monounsaturated, polyunsaturated) …
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PNPLA3 P.I148M VARIANT INCREASES LIPID DROPLETS NUMBER AND SIZE IN PATIENT-DERIVED LIVER ORGANOIDS
… and exposed to 300 μM Palmitic and Oleic fatty acids (FAs) for 72h. Lipid droplets (LDs) average size and number (normalized for nuclei) were quantified by NileRed staining and compared between each PNPLA3 genotype. Regardless of FA treatment, M/M Hep-HLOs show increased LDs size when …
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Blocking Immunosuppressive Factors and Taking Advantage of the Nutrient Supply Within the Tumor Microenvironment: Pathways to Achieve Improved Cancer Immunotherapeutic Efficacy for Patients With Metastatic Melanoma
… in late stage tumors increasingly depend on fatty acids (FAs) catabolism for energy production. Promoting FA catabolism by CD8+TILs improves their effector functions and capacity to delay tumor growth. Overall, my studies show that blocking inhibitory factors while taking advantage of the …
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Metabolomic Insights into the Pharmacological and Genetic Inhibition of Cyclooxygenase-2
… HF. L-Carnitine shuttles activated long-chain fatty acids (FAs) across the inner mitochondrial membrane to the mitochondrial matrix, where they are oxidised by β-oxidation. This is especially important in the heart, which derives the majority of its energy from the metabolism of FAs. Changes in …
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Functional Characterization of Serine Hydrolases Mediating Lipid Metabolism and Protein Depalmitoylation in Asexual Stage Plasmodium Falciparum
… (LPLs) essential for acquiring fatty acids (FAs) from the host. Identifying essential metabolic enzymes will benefit the treatment to malaria. We focused on metabolic SHs and identified two SHs were refractory to knock out. We studied a likely essential SH named PfABHD17A, which …
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Effect of fatty acids and programming on the immune system
Research to date has suggested that fatty acids (FAs) may affect the immune system, through their (and those of their metabolites) effects on membranes, mediators, and gene expression. However, despite the research carried out, there still exist gaps of knowledge where further research is required. …
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Maternal Immune Markers In Serum During Late Gestation and In Breast Milk and the Risk of Asthma-Like Symptoms At Ages 6 and 12 Months: A Longitudinal Study
… (AS) in infancy, and the association between fatty acids (FAs) in colostrum and breast milk with AS and atopy. A second goal is to conduct cluster analyses to obtain different immune marker profiles in serum and in whey in order to estimate the risk of these immune clusters for AS in …
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Protein kinases in hormonal regulation of adipocyte metabolism.
… and use it as a substrate for synthesis of new fatty acids (FAs) in a process known as de novo fatty acid synthesis, as well as for synthesis of glycerol. Adipocytes also take up fatty acids from the circulation and incorporate both newly synthesized and imported FAs into triacylglycerides …
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Characterizing the Binding Potential, Activity, and Bioaccessibility of Peroxisome Proliferator Activated Receptor Gamma (PPARγ) Ligands in Indoor Dust
… NP-HPLC fractions. In the most active fractions, fatty acids (FAs) were identified as the most active chemicals. The concentrations of four FAs were measured in the house dust extracts, and the concentrations were found to be highly correlated with the observed PPAR activity. These four FAs were …