Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Fatty acid-binding proteins"”.
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Design and synthesis of novel compounds as fatty acids binding protein inhibitors and as gallium-68 chelators for positron emission tomography
… discussed. In the first one, the design of new Fatty acid binding protein 4 inhibitors is discussed. In the second one, the design of two targeting peptide bioconjugates for the detection of cancers is reported. Fatty acid binding proteins are a class of proteins involved particularly in the …
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Molecular Biophysics of Mammalian and Fungal Macromolecular Assemblies
… and subsequent conformational changes of fatty acid-binding proteins (FABPs) when bound to a specific substrate, the objective of which was to gain valuable insight on how FABP-ligand interactions impact human obesity. Chapter Two details the study of the macromolecular architecture of the …
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Elucidating Mechanisms of Biofluorescence and Bioluminescence in Marine Organisms
… research presented here will look at separate proteins to uncover their molecular interactions that lead to light generation. We combine transcriptomics, phylogenetics, and biochemical assays to unravel these mysteries. We have studied fluorescent fatty acid binding proteins to discover which …
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Inclusion of Olive or Coconut Oil in a High-Fructose High-Fat Diet Increases Liver Injury in a Pig Model of Pediatric NAFLD
<p>Non-alcoholic fatty liver disease (NAFLD) represents the major cause of pediatric chronic liver pathology in the United States. The objective of this study was to investigate the effect of partial substitution of dietary lard by an isocaloric amount of olive or coconut oil on endpoints of NAFLD. …
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Systemic and Intracellular Trafficking of Long-chain Fatty Acids in Lactating Dairy Cattle
… are used as ration additives to provide omega-3 fatty acids to dairy cows. Supplementing dairy cows with omega-3 fatty acid-rich feeds does not easily increase quantities in milk fat of dairy cows because polyunsaturated fatty acids are biohydrogenated in the rumen. Lipid encapsulation of omega-3 …
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Role of IGF-II, PRL, and FABPs in the Breast Cancer Disparity among AA Women
… stimulates the expression of intracellular fatty-acid binding protein 3 (FABP3). FABP3 is detected in human breast tissue and is known as mammary-derived growth inhibitor (MDGI) because it has a strong inhibitory effect on cell proliferation. FABP5 is also expressed in the breast, and has …