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Showing 1 to 20 of 72 for “"Fatty Acid Synthesis"”.
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Fatty Acid Synthesis in the Rabbit
Made available in DSpace on 2015-05-12T22:36:30Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7511780.PDF: 3160530 bytes, checksum: fac883b50d775cccba5af5f8d1506adb (MD5) Previous issue date: 1974
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Fatty Acid Synthesis in the Bovine Mammary Gland
Made available in DSpace on 2014-12-10T17:37:55Z (GMT). No. of bitstreams: 1 7013240.pdf: 2582037 bytes, checksum: b78b71b75f4f9d4841b93b61a1bba757 (MD5) Previous issue date: 1969
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Regulation of fatty acid synthesis in enterococcus faecalis
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2023-09-01 without embargo terms
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Hepatic Fatty Acid Synthesis and Its Regulation in the Growing Chick
Made available in DSpace on 2015-05-12T22:36:26Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7115007.PDF: 4791416 bytes, checksum: 7cd6800a1fd39669eb83e9dc0e09a670 (MD5) Previous issue date: 1970
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Determination of fatty acid synthesis intermediates in escherichia coli and bacillus subtilis
… of the dry cell weight in bacteria with their synthesis requiring 32 moles of ATP per mole of lipid. This significant investment ensures that the flux through the fatty acid biosynthesis (FAS) and related metabolic pathways is very precisely coordinated. A key feature of the FAS pathway is the …
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Peroxisome Proliferator -Activated Receptor (Ppar)alpha Regulation of Highly Unsaturated Fatty Acid Synthesis
… and confers pathway specific induction of HUFA synthesis by EFA deficient diets. LysoPL may act as signaling molecule and activate PPARalpha in response to essential fatty acid deficiency.
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Identification of molecular targets regulating fatty acid synthesis in bovine mammary epithelial cells
… consuming a high saturated fat diet. Milk fat synthesis is energetically expensive for the dairy cow, especially during early lactation or periods of poor nutrition. Thus, manipulating milk fat production and composition may promote the synthesis of more market-valuable milk components and …
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Regulation of Volatile Fatty Acid Synthesis in Megasphaera Elsdenii and Hexanoic Acid Utilisation by Pseudomonas Putida
… two studies on processes that may lead to adipic acid production through hexanoic acid synthesis pathway by the anaerobic bacterium Megasphaera elsdenii and its subsequent utilisation by Pseudomonas strains. The first part of the research described was concerned with the ability of Pseudomonas …
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Activity and mRNA abundance of enzymes for fatty acid synthesis and desaturation in mammary cell cultures
The effect of exogenous unsaturated fatty acids on cellular fatty acid biosynthesis in mammary cells was examined. Under normal situations, even though the diet of a dairy cow contains considerable amounts of unsaturated fatty acids, viz. oleic acid (18:1) and linoleic acid (18:2), the major …
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Aspects of hormonal regulation of hepatic carbohydrate and lipid metabolism
… glycogen and triglyceride. Hepatic rates of fatty acid and<br/>glycogen synthesis were measured y vivo in response to meal-feeding<br/>(2h/day) by the incorporation of from 3H20. This technique has not<br/>been applied previously to glycogen synthesis and was validated in control<br/>and …
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Novel Metabolic Regulation of Invadopodia and Invasion by Acetyl-CoA Carboxylase and Lipogenesis
… and function, the contribution of de novo fatty acid and phospholipid synthesis has not been elucidated. The data in this dissertation demonstrates the requirement of fatty acid synthesis for the generation and function of invadopodia. Inhibition of acetyl-CoA carboxylase (ACC), the …
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FATTY ACID SYNTHASE MODULATES MAMMARY GLAND LACTATION AND PROSTATE CANCER PROGRESSION IN VIVO
Fatty acid synthesis is the process of producing de novo fatty acids from carbohydrate and protein carbon sources. The enzyme responsible for this task is appropriately termed Fatty Acid Synthase (FASN). FASN is ubiquitously expressed throughout the body, but because fatty acid synthesis is a very …
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Characterization of beneficial mutations in unsaturated fatty acid biosynthesis that are recurrent dead-ends in a long-term evolution experiment with Escherichia coli
… with mutations in the gene coding for the lipid synthesis repressor, fabR, gain traction within the population, but always eventually go extinct. To parse out the fitness benefits and downstream effects, strains with these mutations were constructed. These mutations increase the growth rate and …
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Quantitative analysis of carbon fluxes for fat biosynthesis in wild-type and IRS-1 knockout brown adipocytes
Excessive fat synthesis and the subsequent dysregulation of lipid metabolism constitute the major pathological factors of obesity and type 2 diabetes through triggering insulin resistance. Thus, controlling fat synthesis by identifying key sites for regulation of lipogenesis and modulating the …
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ACETYL COA CARBOXYLASE 1 IN PROSTATE CANCER AS A CHEMOTHERAPEUTIC TARGET
… host of cancer types are known depend on de novo fatty acid synthesis to support aberrant proliferation and survival with prostate cancer being a noted example. The data in this dissertation describes the requirement of acetyl-CoA carboxylase 1 (ACC1), the rate-limiting step of de novo fatty acid …
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Biotin synthesis in Bacillus subtilis
… diversity in pathways lies in the first stage of synthesis of a pimelate thioester moiety. Bacillus subtilis represents a group of microorganisms that follow a different pathway for biotin synthesis. Genetic and biochemical studies identified bioW and bioI as two genes required for pimeloyl-CoA …
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Lipid Metabolism in Corn Tissue Culture and Molecular Biology of Soybean Seed Maturation
… lines resistant to cerulenin, an inhibitor of fatty acid synthesis. While it was hypothesized that the cerulenin-resistant calli might be an overproducing-oil line, the selected resistant calli did not exhibit an increase in lipid content relative to the control calli.
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Raman spectroscopic analysis of fatty acids in tumor micro- and macroenvironments in breast cancer
Fatty acids play essential roles in the growth and metastasis of cancer cells. To facilitate their avid growth and proliferation, cancer cells not only alter the fatty acid synthesis and metabolism intracellularly and extracellularly, but also in the macroenvironment via direct and indirect …
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Modular pathway engineering of microbial fatty acid metabolism for the synthesis of branched acids, alcohols, and alkanes
… Here we report the engineering of microbial fatty acid synthesis to provide both CoA-dependent and fatty acid synthase platforms for previously undescribed routes to medium-chain length, branched acids. Specifically we produced six-carbon 4-methyl-valeric acid via a CoA-dependent route and …
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