Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Fast Exchange"”.
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Nuclear Magnetic Resonance Under Extreme Conditions: High-Pressure NMR Probe Development, and NMR Applications to the Dynamics of Confined Liquids
… measured and analyzed in terms of the two-state-fast exchange model, which allows separation of the surface layer relaxation rates. The experiments showed that the hydrocarbon fluids form stronger hydrogen-bond interactions with the silica surface, and that confinement has little effect on the …
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Solution Properties of Some Iron and Copper Macrocycles.
… shift data for the complexes in DMSO indicate fast exchange and small hyperfine coupling constants. Solution magnetic susceptibilities of the complexes in DMSO indicate the absence of dimers.
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Deuterium NMR relaxation studies of liquids in confined geometries
… data are analyzed by using the two-state fast-exchange model which is found to be valid for the strongly interacting liquids and liquids with intermediate interactions. In terms of this model, the viscosity of the surface layer for pyridine-d$\sb5$ is about 30 times higher than that for …
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Mechanistic studies of bleomycin-mediated double-stranded DNA cleavage and structural studies of DNA containing normal and 4'-oxidized abasic sites
… The resulting mixture of complexes was in fast exchange on the NMR time scale, which precluded further structural characterization.
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Solution Structure of the Apocalmodulin/neuro-P Complex
… magnetic resonance (NMR). This complex is in fast exchange with its components on the NMR timescale, and the dissociation constant for the complex is in the micromolar range. This thesis presents the solution structure of the apoCaM. Neurop complex. The 1H, 13C, and 15N resonance assignments …
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Molecular structure, dynamics and hydration studies of soybean storage proteins and model systems by nuclear magnetic resonance
… assigned. Relaxation measurements indicated fast motion for several side chains and the protein backbone. Protein fractions (11S and 7S) were also investigated at various states of molecular association. The large size of the multisubunit soybean storage proteins affected adversely both the …
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Structural basis of membrane targeting and regulation of the innate immunity adaptor TIRAP by its phosphoinositide-binding motif
… reveal that TIRAP PBM binds PIPs following a fast exchange regime with a moderate affinity through two conserved basic termini. Mutation of these two basic regions abolishes PIPs binding without distorting the helical structure of the peptide. Solution NMR structure of TIRAP PBM exhibits a …
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The Application of Nuclear Magnetic Resonance Towards Understanding Chromatographic Separations of Proteins
… the model system. Poros 50 HS is a strong cation exchange resin frequently used in industry, with an average particle size of 50 μm and bi-disperse pore distribution of so-called micro- and macro-pores. NMR behaviours of the buffer mobile phase within the chromatography column were first …
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Thermodynamics and kinetics of ion-exchange in perchlorate-selective poly(vinylbenzyltrialkylammonium chloride) matrices
Perchlorate-selective ion-exchange fiber composites (IXFCs) based on an active resin-on-fiber architecture exhibit rapid exchange kinetics. Coatings consist of hydrophobic poly(vinylbenzyltrialkylammonium chloride) (PVBTC) matrices prepared by quaternization of a poly(vinylbenzyl chloride) …
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Pseudorotaxanes and Supramolecular Polypseudorotaxanes Based on the Dibenzo-24-Crown-8/Paraquat Recognition Motif
… of apparent association constants, Ka,exp, of fast exchange host-guest systems was studied for the first time by using complexes based on viologens and crown ethers as examples. While the bis(hexafluorophosphate) salts of paraquat derivatives are predominantly ion paired in acetone (and other …
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Structural and Functional Basis for the Autoregulation of the Adaptor Protein TOM1
… TOM1 VHS interacts with PtdIns5P following a fast-exchange regime, with the PtdIns5P binding site predicted to be at a region spanning α-helices 6 to 8. Further mutagenesis and lipid-protein overlay assay studies indicated that K147 plays a critical role in the binding of TOM1 VHS domain to …
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Design and synthesis of new metallo-organic complexes and their evaluation as anti-cancer agents. Synthesis, characterisation and biological evaluation of novel, late first row transition metal schiff base complexes, as anti-cancer metallopharmaceuticals
… are likely either tetradentate in solution or a fast exchange between imine N-donar sites is occurring even down to -65°C. The majority of the resulting complexes of L1R were screened against a panel of three cancer cell lines. Several categories of complex were able to afford structure activity …
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Vapour-Liquid Equilibria within Nanoporous Media
This thesis is dedicated to the exploration of fluid phases confined in nanoporous materials using Nuclear Magnetic Resonance (NMR) techniques, with an aim to benefit catalysis research. Included in this report are studies of pure fluids and their mixtures, confined in titania and silica catalyst …