Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 1 of 1 for “"Fasamycin"”.
-
Studies Towards the Discovery of Novel Natural Products Through Functional Analysis of Environmental DNA-Encoded Type II Polyketide Synthases
… the mode of action of eDNA encoded antibiotics Fasamycins A and B. To identify the target of the fasamycins, fasamycin A resistant mutants were generated. Next generation sequencing of these mutants, along with in vitro biochemical assays, showed that fasamycins inhibit the FabF gene of the type …