Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 282 for “"Fas"”.
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REGULATION OF Fas-MEDIATED APOPTOSIS BY THE Fas ANTI-SENSE NON-CODING RNA "Saf"
… One major apoptotic pathway is triggered by Fas receptor (Fas)-Fas ligand (FasL) interaction. Resistance to Fas-mediated apoptosis is regulated through the production of a soluble Fas isoform (sFas), created by exclusion of transmembrane spanning sequences encoded within exon 6 (FasΔ6) that …
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Doppelt negative T-Lymphozyten, löslicher FAS Rezeptor und löslicher FAS Ligand bei Kindern mit häufigen Infektionen
… wurden die Plasmaspiegel der Plasmaproteine sFas und sFasL. Der prozentuale Anteil an DN-T-Zellen lag signifikant über dem der gesunden Kontrollen bei gleichzeitig erniedrigten CD8 positiven Zellen. Es wird angenommen, dass aktivierte T-Lymphozyten über die Zwischenstufe der DN-T-Lymphozyten …
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FAS Knowledge of Past Pregnant Women
… South Dakota WIG clinics were surveyed using a FAS knowledge test. In this sample, 90% (N=99) of the subjects reported abstinence and 10% reported some alcohol drinking during their pregnancy. FAS knowledge was poor in 16%, moderate in 67%, and good in 17% of the sample. Significant …
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Untersuchung der Rolle des Fas/FasL-Systems bei der Auslösung der Apoptose durch Tumorzellen in Fas-knock out-Makrophagen
… der Apoptosemarker bcl-2, bcl-xL und bax zu erfassen und zu quantifizieren. <br>Ein besonderer Schwerpunkt lag auf einem Vergleich zwischen Kontroll- und Versuchsmakrophagen. Letztere wurden mit Tumorzellüberstand (TZÜ) inkubiert. Die Analyse der Ergebnisse dieser beiden Arbeiten zeigte, dass …
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Attachment and Emotion Regulation in Adolescents with FAS-Dysmorphism
Children with fetal alcohol spectrum disorders (FASD) are frequently reported by caregivers and teachers to have difficulties in socio-emotional functioning. It has been suggested that deficits in emotion regulation underlie these deficits in socio-emotional functioning. Children with prenatal …
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Molecular studies of Fas signaling and programmed cell death
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Biology, 1998.
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JNK regulates Fas receptor mediated apoptosis in prostate cancer cell lines
… elevated resistance to many cytotoxic drugs. The Fas receptor is a membrane bound protein capable of binding to a ligand called Fas ligand. Engagement of Fas receptor with Fas ligand results in clustering of Fas receptor on the plasma membrane of cells. A number of proteins responsible for …
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Characterisation of the role of Fas in intestinal inflammation and cancer
Background: The role of Fas (CD95) and its ligand, Fas ligand (FasL/CD95L), is poorly understood in the intestine. Whilst Fas is best studies in terms of its function in apoptosis, recent studies suggest that Fas ligation may mediate additional, non-apoptotic functions such as inflammation. Toll …
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The Role of Nucleolin In B-Cell Lymphomas and Fas-Mediated Apoptotic Signaling
<p>The death receptor Fas has a key role in mediating homeostasis, elimination of defective cells and more recently implicated in cancer promotion. Many effective anti-cancer therapies depend on Fas-mediated apoptosis to eradicate tumor cells and ineffective Fas-apoptotic signaling is a basis for …
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Role of Fas/FasL, inflammatory mediators and LPS-activated macrophages in human neutrophil apoptosis
… hastening resolution of inflammation. The Fas death receptor pathway is important in T lymphocyte apoptosis but its role in neutrophil apoptosis is controversial. We have shown that neutrophils express the Fas receptor (CD95) on their surface but there is no evidence of expression of its …
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Fas-induced apoptosis: dephosphorylation and cleavage of the retinoblastoma protein leads to cell cycle arrest
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Biological and computational tools for systems biology : application to Fas signaling pathways in T cells
… to a biological and mathematical analysis of Fas signaling pathways in T cells.
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Role of CD44, Fas Ligand, and Perforin in the Cytotoxicity Mediated by Natural Killer Cells
… cytotoxicity, one perforin based and the other Fas ligand (FasL) based, have been characterized recently. It has also been shown that CD44, an adhesion molecule, can participate in signaling cytotoxic activity of cytotoxic T lymphocytes (CTLs). In the current study we tested the hypothesis that …
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Fas ligand expression and tumour immune evasion; the role of prostaglandin E2 and the EP1 receptor
… the anti-tumour immune response. Upregulation of Fas Ligand (FasL/CD95L) expression may represent one such mechanism. FasL is a member of the tumour necrosis factor superfamily that triggers apoptotic cell death following ligation to its receptor Fas. Numerous studies have demonstrated upregulated …
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How the fas locus contributes to Rhodococcus fascians cytokinin production: an in-depth molecular and biochemical analysis
… themselves. The Actinomycete Rhodococcus fascians provokes the formation of differentiated leafy galls consisting of numerous shoot primordia that are inhibited in further outgrowth. Based on the shooty phenotype and the presence of an ipt gene on the linear virulence plasmid of R. …
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Experimentelle Untersuchungen zur Interaktion von Fas mit seinem Liganden an normalen und neoplastischen Zellen des lympho-hämatopoetischen Systems
Fas-Ligand (FasL) stellt einen der 2 Effektormechanismen dar, mit dem T-Zellen den programmierten Zelltod induzieren. Die FasL-Expression auf Tumorzellen wurde in letzter Zeit als ein möglicher Mechanismus angesehen, mit dem sich Tumorzellen der Immunantwort des Körpers entziehen. Die Datenlage …
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Additional costs of FAS and PFAS learners in the classroom: An estimate for public primary schools in the Western Cape
… rates of Fetal Alcohol Spectrum Disorders (FASD) in the world. In the last decade rates of fetal alcohol syndrome (FAS) and partial fetal alcohol syndrome (PFAS) prevalence of 68.0 - 89.2 per 1000 (May et al., 2007), 67.2 per 1000 (Urban et al., 2008), and 59.3 - 91.0 per 1000 (May et al., …
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