Global ETD Search

PRE-CLINICAL MODELING OF CELL AND GENE THERAPY OF FANCONI ANEMIA

Liu, Suying2024

… mice. Applying this method to a FA mouse model, Fancc-/- mice, I revealed that these mice maintain normal levels of precursor cells despite repopulation defects post-transplantation. The only exception was in recipients transplanted with bone marrow from aging Fancc-/- mice, which displayed …

penn Repository record for PRE-CLINICAL MODELING OF CELL AND GENE THERAPY OF FANCONI ANEMIA (opens in a new tab)

Role of Fanconi anemia type C (FANCC) and its cooperation with tumor suppressor P53 in cell cycle checkpoint control, apoptosis, and tumorigenesis

Freie, Brian W.2003

iupui Repository record for Role of Fanconi anemia type C (FANCC) and its cooperation with tumor suppressor P53 in cell cycle checkpoint control, apoptosis, and tumorigenesis (opens in a new tab)

Genomic changes in Fanconi anemia: implications for diagnosis, pathogenesis and prognosis

Groß, MichaelaUniversität Würzburg

… biochemical function(s) remain unknown. FANCA, FANCC, FANCE, FANCF and FANCG interact in a nuclear complex upstream of FANCD2. Complementation group FA-D1 was recently shown to be due to biallelic mutations in the human breast cancer gene 2 (BRCA2). After DNA damage, the nuclear complex …

wurz-thes Repository record for Genomic changes in Fanconi anemia: implications for diagnosis, pathogenesis and prognosis (opens in a new tab)

The Fanconi anemia pathway and HELQ work alongside dormant replication origins to suppress replication-associated genome instability

Luebben, Spencer William2014

… was found to work in parallel to the FA protein FANCC to suppress replication-associated genome instability.

umn Repository record for The Fanconi anemia pathway and HELQ work alongside dormant replication origins to suppress replication-associated genome instability (opens in a new tab)