Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Family Wise Error Rate"”.
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Methods for Using Biomarker Information in Randomized Clinical Trials
… propose two new stage 1 multivariate screening strategies using lasso and ridge regressions to account for correlations among biomarkers. For these new multivariate screening strategies, I prove the asymptotic between-stage independence, required for family-wise error rate control. Simulation and …
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Improving the efficiency of clinical trial designs by using historical control data or adding a treatment arm to an ongoing trial
… treatment effect estimates, inflated type I error and reduced power. We propose two novel weights to assess agreement between the current and historical control data: a probability weight based on tail area probabilities; and a weight based on the equivalence of the historical and current …
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Estimation and Testing Methods for Monotone Transformation Models
… that the new testing procedure controls the family-wise error rate.
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Scalable Estimation and Testing for Complex, High-Dimensional Data
… on manifolds. The first part focuses on a family of parameter estimation problems in which the relationship between data and the underlying parameters cannot be explicitly specified using a likelihood function. We introduce a wavelet-based approximate Bayesian computation approach that is …
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On the finite sample complexity of causal discovery and the value of domain expertise
… implementations of this algorithm incorporate statistical tests for conditional independence, in place of a CI oracle. In this thesis, we analyze the sample complexity of causal discovery algorithms without a CI oracle: given a certain level of confidence, how many data points are needed …
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P-Values For Multiple Testing Procedures
… allows for nonparametric tests to be used to generate P-value statistics satisfying the uniformity condition. The resulting multiple testing procedures are therefore endowed with robustness properties. Simulation studies suggest that nonparametric randomized test P-values allow for multiple …
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FWER controlling procedures for testing multiple hypotheses with hierarchical structure and applications in clinical trials
… procedures is introduced for testing a single family of hypotheses, which allow each hypothesis to be tested even though some early hypotheses in the sequence are not rejected. A condition of a given generalized fixed sequence procedure can strongly control the FWER under arbitrary dependence …