Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Familial risk"”.
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Genetics and familial risk : establishing the clinician's duty to disclose
… Legal System. One of these challenges is the familial nature of genetic information, as screening one individual reveals information about their family unit as a whole. There are potential benefits to disclosing this information, the most important of which is facilitating access to …
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Structural brain imaging in individuals at high familial risk of schizophrenia
… schizophrenia, or in unaffected relatives with a familial vulnerability to develop the disorder, or only in those at high risk that go on to develop the disorder. Furthermore, most studies have been conducted cross-sectionally, which may have obscured subtle longitudinal changes in familial high …
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Genetic Modulation of the Neonatal Neural Processing of Speech at High and Low Familial Risk for Developmental Dyslexia
… deficits in neonates associated with genetic and familial risk of dyslexia. Poor awareness of speech sounds (phonology) is the hallmark of dyslexia, across all languages studied so far. Despite the identification of several dyslexia susceptibility genes, little is known about the mechanisms by …
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The Family Study: Assessment of the Incidence, Etiology, Circumstances and Familial Risk for Sudden Cardiac Death and Aborted Sudden Cardiac Death in Young Individuals
… preventable triggers, and identifiable familial predisposition to fatal arrhythmias. Methods: This study had 3 parts: (1) the development and (2) implementation of a novel, comprehensive methodology to capture all SDs and aborted SDs (both cardiac and non-cardiac) in a defined geographic …
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Sensory Features in Autism Spectrum Disorder: A Systematic Review of Measurement Quality and Empirical Investigation of Sensory Responsivity in Children at High and Low Familial Risk for Autism
… in a sample of children with a high and low familial likelihood for developing ASD, I characterized sensory responsivity in social and non-social contexts early in life and investigated the development of sensory responsivity throughout childhood with considerations for variables that may …
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Cognitive functioning in familial and nonfamilial groups at high-risk for schizophrenia
… clarify the cognitive deficits that characterize familial and nonfamilial groups at high-risk for schizophrenia. High-risk was defined as (1) Genetic relatedness to an individual with schizophrenia, or (2) Extreme scores on a measure of schizotypy (i.e., Chapman Scales of Psychosis Proneness). …
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Inherited risk for common disease
… offered that complex modes of inheritance govern risk for cancers, cardiovascular and cerebrovascular diseases, and diabetes. Such studies, however, depended on the untested assumption of monoallelic risk. My research advisor and I set out to investigate whether simple forms of inherited risk, …
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A Comprehensive Genetic Risk Model for the Prediction of Future Prostate Cancer
The only established prostate cancer (PCa) risk factors are age, ethnic ancestry and family history. Several PCa genetic susceptibility variants have been identified, including rare moderate-to-high risk pathogenic variants (PVs) and common low-risk variants which jointly explain 40% of the excess …
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Coronary Heart Disease Risk Factors in Schoolchildren Aged 12 to 13 Years of Differing Socio-Economic Status
… were assessed for coronary heart disease (CHD) risk factors. Rural (school 1) and valley (school 2) comprehensive schools (age range 11 to 18 years) were selected to represent differing socio-economic status (SES). Informed written consent was sought from head teachers, parents, and …
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The Role of Parent Responsiveness and Vocal Complexity in Expressive Language Outcome: Intervention Effects in Toddlers at Risk for ASD and Language Impairment
… this relation for these toddlers at high familial risk for ASD (high risk; HR toddlers). Also, previous studies have not examined the role of vocal complexity occurring within preverbal (non-word) vocalizations, distinct from that occurring within words. Low preverbal vocal complexity may …
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Female suicidal behaviour: Initiation, cessation and prevention
… when in conjunction with other, mainly familial, risk factors and an absence of protective factors. More significantly, the women noted that the effects of sexual abuse were exacerbated by problems with disclosure. Issues of control emerged as key to both suicidal behaviour and …
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Do caregiving-related stress and emotion regulation impact treatment adherence to a caregiver-mediated intervention for toddlers at risk for ASD?
… ImPACT while delivering it to their toddlers at familial risk for ASD. It was expected that: 1) high levels of caregiving-related stress would predict low levels of treatment adherence; 2) high levels of adaptive ER strategies would predict high levels of treatment adherence; and 3) ER strategies …
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Cognitive Functioning in Alcohol and Other Substance Use Disorders in Young Adulthood : A Genetic Epidemiological Study
… to societal, are associated with elevated risk of SUDs, but at the level of individuals, one of the best predictors is a family history of SUDs. Genetically informative twin and family studies have consistently indicated this familial risk to be mainly genetic. In addition, behavioral and …
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Genetic factors in childhood cancer. Associations between tumors in childhood and adulthood, and prevalence of germline TP53 mutations
… to cancer may be at higher than normal risk for therapy related cancers. Increased knowledge regarding the importance of hereditary factors in the development of childhood tumors may improve the medical care of such patients by identifying those in need of more individualized treatment. …