Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Familial Melanoma"”.
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Chemoprevention of Familial Melanoma
… MBEH can be used for prophylactic treatment of familial melanoma by being specifically toxic to melanocytes and activating an immune response against distant pigment cells. Cytotoxic experiments reveal that similar to 4-TBP, MBEH induces specific melanocyte death. To compare death pathways …
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Identification of germline variants that predispose to familial melanoma
Melanoma is an extremely aggressive malignancy with a poor prognosis in advanced disease. While GWAS and exome analysis have helped to identify loci linked to the development of the disease, these studies have explained predisposition to melanoma in only a fraction of cases. Thus, the majority of …
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Drivers of melanoma susceptibility
Cutaneous melanoma is a cancer of melanocytes, the pigment-producing cells in our skin. It is one of the most aggressive human malignancies, constituting only about 2% of all dermatological cancers but being responsible for over 75% of all deaths from skin cancer. It has recently become a major …