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Showing 1 to 1 of 1 for “"Fam60a"”.
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Role of Fam60a in the Regulation of HIF-2α and Determination of Stem Cell Fate
… family with sequence similarity 60, member A (Fam60a) protein is shown to repress expression of the HIF 2α gene through its association with the class 1 Sin3-HDAC co-repressor complex, achieving specificity by co-operation with the SP1 transcription factor. This novel mechanism is demonstrated …