Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"Facial Nerve"”.
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The Development of the Facial Muscles and the Facial Nerve in Human Embryos
… of the muscles in man supplied by the facial or seventh cranial nerve together with the morphogenesis of the extramedullary part of the nerve. The muscles include not only those of facial expression but also the nonmimetic muscles. The development of the facial nerve encompasses the …
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Effects of Electrical Stimulation and Testosterone in Translational Models of Facial Nerve Injury
… nervous system injuries seen clinically, facial nerve lesions are prevalent and have significant functional and emotional impact on patients. As injuries can occur in different segments of the facial nerve and lead to different pathophysiological outcomes, animal models that mimic the …
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Using electrical stimulation responses to understand cochlear implant status
… hearing loss. CIs stimulate the auditory nerve with current pulses on a multi-electrode array that is placed inside the cochlea. Success of CIs varies based on a wide range of patient-related and implant-related factors. In this thesis, I investigate the use of CI electrical stimulation …
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Axotomy and Regeneration of the Rat Facial Nerve: A Histomorphometric Study of the Facial Nucleus, Nerve and Orbicularis Oculi Muscle in an Experimental Model of Facial Paralysis
<p>One of the most unsettling sequela of facial paralysis (FP) is the loss of eye sphincter function and the blink response, leading to functional, psychological and aesthetic deficits. A medley of restorative microsurgery approaches have been employed in treating these deficits, however full …
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Effects of electrical stimulation and testosterone on regeneration-associated gene expression and functional recovery in a rat model of sciatic nerve crush injury
… is often suboptimal following peripheral nerve injury (PNI). Research to date indicates that the greatest success in achieving full functional recovery will require the use of a combinatorial approach that can simultaneously target different aspects of the post-injury response. In general, …
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Multiple roles for Robo1/2 repellent receptors in guiding the facial nucleus and nerve
The facial nerve is necessary for our ability to eat, speak, and make facialgestures. To perform these vital functions, the nerve must accurately navigate from the hindbrain to the correct muscles during embryonic development. In the development of the facial nerve, both the cell bodies and the …
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Effects of Electrical Stimulation and Testosterone in Translational Models of Peripheral Nerve Injury
<p>As functional recovery following peripheral nerve injury is dependent upon successful regeneration and target reconnection, combinatorial treatments that enhance different regeneration events may be required for recovery from severe injuries. The neurotherapeutic effects of electrical …
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Kazuistika fyzioterapeuticke pece o pacienta s diagnozou paréza nervus facialis
… care for a patient diagnosed with peripheral facial palsy Aim of the thesis: The aim of the thesis is to present theoretical information about the peripheral facial nerve palsy diagnosis. Further, the practical part of the thesis describes the use of chosen physiotherapeutic ways of the …
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Migration of human tympanic epithelium in health and disease
… <i>cholesteatoma*</i>, can, in turn, invade the facial nerve, inner ear and intracranial contents and require surgical intervention which in itself poses some risk to the individual. <br></br><br></br>The probable origins of cholesteatoma have been debated for more than a century. …
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Molecular Expression of Neuroprotective and Neurodestructive Signaling Systems Following Axotomy-Induced Target Disconnection: Relevance to ALS
… MN degeneration. Our lab utilizes a peripheral nerve injury model to investigate the mechanisms of MN survival in the pre-symptomatic SOD1 mouse. We have shown SOD1 mice display enhanced facial MN (FMN) cell loss following a facial nerve axotomy, compared to wild-type (WT) mice. Analysis of gene …
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Untersuchung molekularer Reaktionen nach zentralen und peripheren Nervenläsionen bei der Ratte unter besonderer Berücksichtigung von Neurodap1
… describes the molecular reactions to regenerate nerve cells after lesion of the spinal cord in rats. Special emphasis is laid on the differences between the central and peripheral nervous systems, since the central system is not able to regenerate after axotomy. In particular, we wanted to …
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Immunoregulation of the central response to peripheral nerve injury: motoneuron survival and relevance to ALS
Facial nerve axotomy (FNA) in immunodeficient mice causes significantly more facial motoneuron (FMN) loss relative to wild type (WT), indicating that the immune system is neuroprotective. Further studies reveal that both CD4+ T cells and interleukin 10 (IL-10) act centrally to promote neuronal …
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From bench to bedside : elucidating vestibular schwannoma pathobiology to devise effective pharmacotherapies
… arise from Schwann cells of the vestibular nerve. VSs can lead to sensorineural hearing loss (SNHL), disequilibrium, facial nerve paralysis, and brainstem compression. Treatment options available today are associated with significant morbidity, leading to an unmet need for well-tolerated …
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Bell's Palsy - Medical Treatment and Influence of Prognostic Factors
Bell’s palsy is an acute onset of peripheral facial nerve dysfunction. Despite extensive research the aetiology is unclear. The most prevailing theory is that reactivation of viruses such as Herpes simplex type-1 or Varicella zoster may cause Bell’s palsy. The natural course is favourable but at …
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Chirurgische Behandlung des Akustikusneurinoms : prä- und postoperative Funktion des Nervus facialis
… Zustandes gebeten. Darüber hinaus wurden Facialisneurographien mit elektrischer und magnetischer Stimulation auf ihren prädiktiven Wert bezüglich der langfristigen Funktion des Gesichtsnerven untersucht.
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Funktionelle Ergebnisse des Nervus facialis nach transtemporaler und translabyrinthärer Resektion von Akustikusneurinomen
… mit Untersuchungen des Funktionserhalts des N. facialis nach transtemporaler und translabyrinthärer Resektion von Akustikusneurinomen. Es wurden retrospektiv 477 Patienten in Bezug auf anamnestische Daten, Tumorlokalisation und -größe, sowie die prä- und postoperative Fazialisfunktion erfasst, …
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Genetische Untersuchungen zur Rolle von Cytochrom C und Stat3 bei der Regulation des embryonalen Zelltods von Motoneuronen der Maus
… die Rolle von Cytochrom C bei der Apoptose von Nervenzellen in vivo durch genetische Inaktivierung in der Maus zu untersuchen. Die homozygote Deletion des Cytochrom C Gens führt jedoch zu einem sehr frühen Entwicklungsdefekt: Schon am 8. Embryonaltag findet man nur noch Embryonen ohne erkennbare …
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Perineural Invasion in Oral Squamous Cell Carcinoma and Salivary Gland Malignancies: Incidence, Prognostic Impact and Molecular Insight
… from a reciprocal interaction between tumour and nerve, probably due to some cellular factors and their respective receptors. A number of neurotrophic factors such as nerve growth factor (NGF) and its high affinity tyrosine kinase A (TrkA) receptor have been identified as being possibly of …
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Histomorphometrische Untersuchung zur gerichteten Nervendistraktion anhand des Nervus Facialis der Ratte
… moduliert gerichteten und gesteuerten primären Nervendistraktion bei der Ratte. Unter Ausnutzung der bei der Nervendegeneration und ihrer Regeneration bisher gewonnenen Ergebnisse sollten die Technik zur Durchführung und der Grad der degenerativen Veränderungen des Nerven nach der moduliert …
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