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Showing 1 to 2 of 2 for “"FVIIai"”.

  1. Crosstalk between Inflammation and Coagulation in Acute Pancreatitis - Experimental and Clinical Studies.

    … first paper, where active site inactivated FVII (FVIIai) is given as pre-treatment in a rat model of severe AP, show a decreased inflammatory response in the FVIIai pre-treated animals. In the second paper the activation of nuclear factor kappa B (NFκB) is studied in the rat model of severe AP. …

    lund Repository record for Crosstalk between Inflammation and Coagulation in Acute Pancreatitis - Experimental and Clinical Studies. (opens in a new tab)

  2. INITIATION OF EXPERIMENTAL ACUTE PANCREATITIS AND MODULATION OF INFLAMMATORY RESPONSE

    … anti-coagulant active site-inhibited factor VII (fVIIai) was shown to drastically decrease the inflammatory response. The effects in reducing neutrophil infiltration differed substantially between different organs. Nuclear factor kappa B (NFκB) activation was also shown to be affected by fVIIai. …

    lund Repository record for INITIATION OF EXPERIMENTAL ACUTE PANCREATITIS AND MODULATION OF INFLAMMATORY RESPONSE (opens in a new tab)