Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"FSCV"”.
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Improving dopamine monitoring with NCAM and the effects of intranasal oxytocin on dopamine signaling in the rat brain
… and memory. Fast-scan cyclic voltammetry (FSCV) is a method used for the real-time examination of DA neurotransmission in the brain. Implanting FSCV electrodes is an invasive technique that likely results in an inflammatory response (i.e. gliosis) that can restrict FSCV recording of DA …
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A Novel, Ultra-Fast Electrochemical Tool To Study Speciation Of Trace Metals In Aqueous Solution
… the underlying mechanisms of the ultra fast FSCV response. Adsorption was explained as the fundamental mechanism for the rapid FSCV signal and the thermodynamic properties of adsorption of Cu2+ onto CFMs were evaluated with fast scan controlled adsorption voltammetry in different matrices. In …
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The influence of anesthesia and nicotine on dopamine signaling in the rat dorsal striatum
… striatum). Fast-scan cyclic voltammetry (FSCV) is a technique that uses microelectrodes (diameter ~5 μm, length ~150 μm) to monitor dopamine signaling in the brain. Although urethane and isoflurane anesthetics are commonly used in in vivo studies, isoflurane’s potential influence on …
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Development Of Single And Array Electro-Chemical Sensors For Real-Time Trace Metal Analysis In Aqueous Environmental Media
… a method using fast-scan cyclic voltammetry (FSCV) at carbon-fiber microelectrodes (CFMs) to achieve rapid measurement of metal ions with high sensitivity, selectivity, and stability. Through optimizations this method showed strengths in real-time trace metal analysis. </p> …
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Novel Electrochemical Methods for Human Neurochemistry
… adapted fast scan cyclic voltammetry (FSCV) from rodent experiments for use in human patients already receiving brain surgery. The process of modifying established FSCV methods for clinical application has led improved model building strategies, and a new "random burst" sensing …
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Long-term characterization of the chronic dopamine microelectrode and effect of electrical conditioning
… and addiction. Fast-scan cyclic voltammetry (FSCV) has long been an indispensable tool for monitoring real-time DA signaling. Development of polyimide fused silica-encased FSCV microelectrodes have made the technique more suitable for chronic DA monitoring (months) in vivo. Methods: In this …
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Effect of low endogenous brain-derived neurotrophic factor levels on striatal dopamine dynamics
… slice (in vitro) fast scan cyclic voltammetry (FSCV) and in vivo microdialysis were used to characterize striatal DA dynamics in wildtype and BDNF heterozygous mutant (BDNF+/-) mice. </p> <p>Overall, our findings highlight that (1) we were able to develop a reliable FSCV assay to characterize DA …
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Evaluation Of Presynaptic Dopamine Dynamics After: Toluene Inhalation Or Trkb Receptor Activation
… such as slice fast scan cyclic voltammetry (FSCV), in vivo microdialysis, and brain tissue content analysis to examine how toluene inhalation alters the striatal DA system. Overall, both behavior and neurochemical data confirmed that toluene inhalation alters stimulated DA release in …
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Functional Alterations in the Dopamine Transporter of Rodents following Self-Administration of Cocaine, Heroin and Speedball
… synergism, in vivo fast-scan cyclic voltammetry (FSCV) was used to compare evoked DA release and DA transporter (DAT)-mediated reuptake kinetic parameters following acute administration of cocaine, heroin and speedball in drug-naïve rats, as well in rats with chronic self-administration (SA) …
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Microfabrication and Electrochemical Characterization of a Novel SU-8 Probe with an Array of Individually Addressable Electrodes Suitable for Redox Cycling Experiments in Ultra-small Volumes
… rat brain indicates minimal damage comparable to FSCV electrodes and less extensive than the microdialysis probe.</p> <p>The electrodes on the probe were characterized electrochemically and redox cycling on the array was evaluated in vitro in the presence of model compounds (potassium ferricyanide …