Global ETD Search
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Showing 1 to 2 of 2 for “"FP domain"”.
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STRUCTURAL AND FUNCTIONAL STUDIES OF F-BOX-ONLY PROTEIN FBXO7 AND ITS INTERACTIONS WITH PROTEASOME INHIBITOR PI31
… is mediated by heterodimerization of the FP domains of the two proteins. This work is focus on study the protein structure of the two FP domains in Fbxo7 and PI3. Chapter 1 reviewed the F-box-only protein Fbxo7 biology including the function of Fbxo7 protein in ubiquitination proteasome …
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Post-translational control of mitochondria by Fbxo7 in Parkinson's disease
… function is as the substrate recruiting domain of an E3 SCF ubiquitin ligase complex. Mitochondrial defects have previously been detected in cells lacking Fbxo7 expression, although the precise mechanisms through which Fbxo7 protects cells from mitochondrial dysfunction and neuronal cell …