Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"FOXO4"”.
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Búsqueda de mutaciones en el gen foxo4 en pacientes con falla ovárica prematura no-sindrómica
FOXO4 constitutes a coherent candidate gene associated with premature ovarian failure (POF) pathogenesis. This study sequenced the coding and exon-flanking regions of this gene in a panel of 116 POF patients and 143 controls of Tunisian origin. In both groups, the IVS2 + 41T > G sequence variant …
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Study of Mutations and Expression of Genes Correlated to the Appearance of Colorectal Cancer /// Проучване на мутации и експресия на гени, корелиращи с изявата на колоректален карцином
… • Analysis of the expression levels of SIRT6, FOXO4 and HIF3A genes of all patients’ tumours compared to healthy colon tissue and correlation to RAS mutational status and according to patient staging. • Correlation between the expression of SIRT6, FOXO4 and HIF3A genes in all patients’ tumours, …
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Foxo Transcription Factors Control Spermatogonial Stem Cell Self-Renewal and the Initiation of Spermatogenesis
… with limited contributions from Foxo3 and Foxo4. Conditional inactivation of PI3K/Akt pathway components in the male germ line confirmed that PI3K signaling regulates Foxo1 stability and subcellular localization, revealing that the Foxos are crucial effectors of PI3K/Akt signaling in SSCs. …
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The Role of Foxo Transcription Factors in B Cell Development and Activation
… homeostasis will be explored. Foxo1, Foxo3, and Foxo4 have both anti-mitogenic and pro-apoptotic properties. The transcription factors are posttranslationally controlled via Akt. When a mature B lymphocyte is stimulated through the BCR, Akt-mediated phosphorylation of Foxos results in their …
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Epidermal Reactions to Injury with Implications for Innate Immunity
… binding sites for forkhead box O1 (FOXO1), FOXO4 and STAT5A, in the most differentially expressed genes in injured skin. This indicates, for the first time, that these transcription factors might play a major role in the wound healing process.
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Identifying circulating biomarkers in a cohort of hypercholesterolaemic patients with statin intolerance from Gauteng, South Africa
… for miR-499a using TargetScan of note is FOXO4, PDCD4 and SOX6, which all are genes associated in pathways related to regulation of smooth and skeletal muscle cell differentiation. Quantitative polymerase chain reaction (qPCR) was used to determine the levels of miR-33a, miR-133a and …