Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"FMRFamide"”.
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Mode of action of FMRFamide-like peptide on drosophila body wall muscle conractions
… from the brain to the cells of all tissues. DPKQDFMRFamide, a member of one of the largest families of neuropeptides, FMRFamide-like peptides, has modulatory effects on nerve-evoked contractions of Drosophila body wall muscles (Hewes et aI.,1998) which are at least in part mediated by the ability …
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Cholinergic and peptidergic responses of pedal A cluster cells of the pond snail lymnaea stagnalis
The cardioexcitatory neuropeptide FMRFamide was first identified and characterised by Price and Greenberg in the mollusc Macrocallista nirnbosa. Since then the peptide has been investigated in species representing every molluscan class except Scaphopoda The main classical neurotransmitters within …
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Peptidergic Signaling Controls the Dynamics of Sickness Behavior in Caenorhabditis Elegans
… screen, I show that the AVK neurons release FMRFamide-like FLP-1 neuropeptides during infection to drive avoidance of pathogenic bacteria. Manipulations that increase or decrease AVK signaling accelerate or delay pathogen avoidance, respectively, implying an instructive role in the behavioral …
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Physiology and pharmacology of flatworm muscle
… manner. The platyhelminth-derived FMRFamide-like peptide (FLP) YIRFamide significantly increased current amplitude at 1muM. YIRFamide's ability to amplify the inward currents was reduced when verapamil was simultaneously present in the perfusion solution, indicating possible VOCCs …
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Serotonin signaling in C. elegans
… 5-HT signaling. We identified two alleles of the FMRFamide-encoding gene fp-1, which was known to mediate paralysis in exogenous 5-HT. We showed that loss-of-function mutations in flp-1 confer an enhanced slowing response defect. We also identified an allele of abts-1, which encodes a bicarbonate …
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Genetic and Neural Circuit Analyses of Sickness and Foraging Behaviors in C. elegans
… drive sickness behaviors. These pathways include FMRFamide peptides and the TGF-beta/DAF-7 neuromodulator, which are released from distinct neural sources and in distinct combinations to drive state-dependent behaviors. In Chapter 3, we reveal the functional architecture of a neural circuit that …