Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 43 for “"FLC"”.
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RNA Therapeutics for Fibrolamellar Hepatocellular Carcinoma
<p>Fibrolamellar hepatocellular carcinoma (FLC) is a rare liver cancer characterized by a recurrent fusion of the heat shock protein DNAJB1 and the catalytic subunit of protein kinase A (PRKACA). Due to limited efficacy of conventional treatments such as chemotherapy and radiation my work explored …
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Analysis and Applications of the Km Algorithm in Type-2 Fuzzy Logic Control and Decision Making
Interval type-2 (IT2) fuzzy logic controller (FLC) is an extension of type-1 (T1) FLC. A large number of experiments have demonstrated that the IT2 FLC can produce more satisfactory performance. However, there has been no rigorous theoretical analysis studying the potential advantage of the IT2 …
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Chromatin-based memory of prolonged cold exposure in Arabidopsis thaliana
… through cell division. FLOWERING LOCUS C (FLC) in the plant Arabidopsis thaliana is repressed by the prolonged cold of winter, and repression is maintained in subsequent warm conditions. The molecular complexes involved in modulating FLC chromatin are vital for FLC regulation and are …
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THE RNA-BINDING PROTEIN LRP1 MEDIATES FLOWERING TIME IN ARABIDOPSIS
… network of genetic pathways. FLOWERING LOCUS C (FLC), a MADS-box transcription factor, is a strong repressor of this flowering process, intricately controlled by several genetic pathways, including the autonomous pathway. We show that LATE FLOWERING RNA-BINDING PROTEIN 1 (LRP1), an RNA-binding …
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Expression Pattern of Drug-Resistance Genes in Matched Clinical Isolates of Candida albicans at Variable Fluconazole Exposure Times
… used to treat these infections is fluconazole (FLC), a fungistatic azole targeting lanosterol 14α-demethylase (Erg11) in the ergosterol biosynthesis pathway. In some clinical isolates, resistance to FLC is due to overexpression of a) the encoding genes CDR1 and CDR2 for the ABC Transporters, b) …
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Proteomic Analysis of WNT Signaling and Metabolism of Fibrolamellar Hepatocellular Carcinoma
<p>Fibrolamellar hepatocellular carcinoma (FLC) is a rare form of liver cancer that primarily affects young adults and adolescents.Although characterized as a subvariant of hepatocellular carcinoma (HCC), we have shown it is distinct based on its pathogenesis, patient population and drug response. …
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Spatiotemporal modelling in biology: from transcriptional regulation to plasmid positioning
… of the floral repressor FLOWERING LOCUS C (FLC ) in Arabidopsis thaliana and spatial positioning of low copy number plasmids in Escherichia coli. Despite the diversity in biological subjects, my spatiotemporal modelling approach provides a common ground. FLC regulation involves an …
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Pathogenic Characterization and Therapeutic Development for Fiblrolamellar Hepatocellular Carcinoma
<p>Fibrolamellar hepatocellular carcinoma (FLC) is a rare liver cancer that primarily affects adolescents and young adults. There are no known successful systemic chemotherapies for this disease, and thus, surgery is the only potential path to a cure in patients with FLC. Once the disease has grown …
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APPLICATION OF ARTIFICIAL INTELLIGENCE TO STATIC VAR SOURCE CONTROL FOR IMPROVING POWER SYSTEM DAMPING
… damping. Two kinds of Fuzzy Logic Control (FLC) based SVC controllers are proposed. The first kind of FLC mechanism is based on the power system oscillation energy analysis and makes use of genetic algorithm to tune the rule base of FLC. The second is based on Lyapunov function analysis and …
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Development and implementation of a methodology for fuzzy logic controller design
… a main fuzzy logic controller refered to as Main-FLC where the initial knowledge about the system is stored. The second main function considers the phase and amplitude of the final control signal. It is called Shay-PA and it implements an implicit on-line tuning and adaptation of the Main-FLC …
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Liver resection for hepatocellular and fibrolamellar carcinoma in a South African tertiary referral centre
… in SSA with HCC. Fibrolamellar carcinoma (FLC) was until recently regarded as a variant of HCC occurring in young patients with a relatively good prognosis but is now recognized as a distinct clinical entity with consistent chimeric fusion protein (DNAJB1-PRKACA) expression by FLC tumours. …
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The field oriented control of a permanent magnet synchrounous motor (PMSM) by using fuzzy logic
… (PMSM) drive system of Fuzzy Logic Controller (FLC) and proportional-integral PI for speed control in closed loop operation. To perform speed control of typical PMSM drives, PI controllers and FOC method are classically used. PI Controller controller suffers from the drawback that for its proper …
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Governor control optimization of hydro power plants using hybrid fuzzy logic and PID control.
… studies on ways to use fuzzy logic control (FLC) together with the conventional proportional-integral-derivative (PID) controllers to aid in this process. However, coming up with the inputs, rule base and the outputs, including a number of each of these in the FLC system has always been …
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Analytical and numerical prediction of localized necking in sheet metal forming processes
… The strain-based forming limit curve (FLC) is one of the tools to predict the maximum permissible strains of thin metallic sheets which are loaded in the plane of the sheet to different states of stress. It may be used to assess forming operations in the press shops as well as …
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Diffraction of point sets with structural disorder
… um Mengen mit beschränkter lokaler Komplexität (FLC-Mengen) in R^d, die zufällig mit Gewichten aus einer kompakten Teilmenge der komplexen Zahlen versehen werden. Der Zufallsmechanismus ist durch eine Klasse von Gibbs-Maßen gegeben. Damit Ergodensätze zur Analyse der Diffraktionsmaße benutzt …
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Dissecting the Role of Hedgehog Pathway in Murine Gonadal Development
… is alone essential and sufficient to induce FLC differentiation. My objective was to address three main questions concerning the role of Hh signaling in gonadal development. In chapter III, I addressed the first question on whether Hh signaling is sufficient to induce FLC differentiation. …
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System identification and control of magnetic bearing systems
… The advanced PD-like Fuzzy Logic Controller (FLC) has also been designed for AMB system stabilisation. The designed FLC can deal with the magnitude and phase fluctuations around resonant frequencies without using notch filters. The performance of the designed FLC has been evaluated via …
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Design Optimization of MagneShock Magnetorheological Shock Absorbers and Development of Fuzzy Logic Control Algorithms for Semi-Active Vehicle Suspensions
… of implementing real-time, fuzzy logic control (FLC) to a vehicle suspension equipped with commercially available magnetorheological (MR) shock absorbers, Carrera MagneShocks™. MagneShocks™ utilize controllable electromagnets to change the MR fluid viscosity and vary the damping characteristics …
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Hybrid fuzzy- proportionl integral derivative controller (F-PID-C) for control of speed brushless direct curren motor (BLDCM)
… in the system. The fuzzy logic controller (FLC) is designed according to fuzzy rules so that the systems are fundamentally robust. There are 49 fuzzy rules for each parameter of FUZZY-PID controller. Fuzzy Logic is used to tune each parameter of the proportional, integral and derivative ( …
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Fuzzy technology application for mobile positioning in cellular communication
… successful applications of Fuzzy Logic Control (FLC) techniques in many areas draw a huge amount of attention to its industrial applications. However, lack of structured methods and tools for design and analysis is preventing this revolutionary controller from playing a more significant role in …
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