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Showing 1 to 4 of 4 for “"FKHR"”.

  1. Der Transkriptionsfaktor FKHR interagiert mit STAT-Faktoren und verstärkt die IL-6-Signaltransduktion

    … possible to identify the transcription factor FKHR as a crosslink molecule between the PI3 kinase/PKB signal transduction pathway and the IL6/gp130/Jak/STAT cascade. The synergism of the transcription factors STAT3 and FKHR could be proven and FKHR was able to increase the IL6 induced STAT3 …

    aachen Repository record for Der Transkriptionsfaktor FKHR interagiert mit STAT-Faktoren und verstärkt die IL-6-Signaltransduktion (opens in a new tab)

  2. The role of PAX3/PAX7-FKHR in mesenchymal stem cell myogenic differentiation and rhabdomyosarcomagenesis

    … or t(1;13) translocations, involving PAX3-FKHR and PAX7-FKHR fusion genes respectively. These genetic events result in a molecular gain of function of the fusion protein, which is proposed to perturb the differentiation of muscle progenitor cells. Since PAX3/7-FKHR fusions result in …

    edithcowan Repository record for The role of PAX3/PAX7-FKHR in mesenchymal stem cell myogenic differentiation and rhabdomyosarcomagenesis (opens in a new tab)

  3. A molecular genetic investigation of rhabdomyosarcoma

    … which leads to the fusion of the P AX3 artd the FKHR genes. The resulting fusion gene encodes a chimeric protein which has aberrant transcriptional activity. The data here describes the molecular definition of the genomic breakpoints on both derivative chromosomes in one case and the derivative …

    the-open-u Repository record for A molecular genetic investigation of rhabdomyosarcoma (opens in a new tab)