Global ETD Search

Analysis of cell cycle surveillance mechanisms in meiosis

Hochwagen, AndreasMassachusetts Institute of Technology2006

… The extent of the delay is modulated by protein phosphatase 1 (PP1), whose activity allows cells to overcome the checkpoint dependent delay in a process called adaptation. In this work, experiments in the budding yeast Saccharomyces cerevisiae are described that show that premature …

mit Repository record for Analysis of cell cycle surveillance mechanisms in meiosis (opens in a new tab)

Biochemical and Structural Studies of the Role of FKBP(L)s in the fly and Mammalian Circadian Cycle

Agyekum, Kwaku BoadiUniversity of Missouri -- Kansas City2017

FK506 binding-like proteins (FKBPLs) are proteins that structurally resemble the immunophilins. Their functions in cell signaling include protein folding, molecular trafficking, RNA splicing and cell cycle regulation among others. Bride of Doubletime (BDBT) previously designated as CG17282 in the …

umkc Repository record for Biochemical and Structural Studies of the Role of FKBP(L)s in the fly and Mammalian Circadian Cycle (opens in a new tab)

Bridging the link between trauma, brain development and depression: epigenetic mechanisms

Chiarella, Julian2016

… at the serotonin transporter (SLC6A4) and FK506 binding protein gene (FKBP5) genes (two genes strongly linked to stress regulation and depression). Second, how does childhood trauma, which is known to increase risk for depression, affect (2a) brain development and (2b) SLC6A4 and FKBP5 …

queens Repository record for Bridging the link between trauma, brain development and depression: epigenetic mechanisms (opens in a new tab)

From symptoms to cells: childhood maltreatment and FKBP5 shape immunocellular bioenergetics in Borderline personality disorder

Neuner, FelixUniversität Ulm

ulm-diss Repository record for From symptoms to cells: childhood maltreatment and FKBP5 shape immunocellular bioenergetics in Borderline personality disorder (opens in a new tab)

Towards understanding EC coupling protein expression with age

Willemse, Hermia2014

… mice but not investigated in humans. The 12kDa FK506 binding protein (FKBP12) stabilizes RyR1 in the closed state. Its dissociation from RyR1 causes a ""leaky"" channel and decreased EC coupling. Furthermore, RyR1 has two variably spliced regions, ASI and ASII, thought to be developmentally …

aus-cath Repository record for Towards understanding EC coupling protein expression with age (opens in a new tab)

Towards understanding EC coupling protein expression with age

Willemse, Hermia2014

… mice but not investigated in humans. The 12kDa FK506 binding protein (FKBP12) stabilizes RyR1 in the closed state. Its dissociation from RyR1 causes a ""leaky"" channel and decreased EC coupling. Furthermore, RyR1 has two variably spliced regions, ASI and ASII, thought to be developmentally …

anu Repository record for Towards understanding EC coupling protein expression with age (opens in a new tab)

Adenovirus-mediated gene transfer of FK506-binding proteins FKBP12.6 and FKBP12 in failing and non-failing rabbit ventricular myocytes

Zibrova, Darya2012

Die FK-506 Bindungsproteine (FKBP) können in Skelettmuskel (FKBP12) und Herzmuskel (FKBP12.6) die Kalziumfreisetzung aus dem sarkoplasmatischen Retikulum (SR) durch Bindung am Ryanodin Rezeptor (RyR) beeinflussen. FKBP12.6 bindet an den kardialen RyR (RyR2) und FKBP12 ausschließlich an den …

goettingen Repository record for Adenovirus-mediated gene transfer of FK506-binding proteins FKBP12.6 and FKBP12 in failing and non-failing rabbit ventricular myocytes (opens in a new tab)