Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"FITC-insulin"”.
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Synthesis and characterisation of fluorescent FITC-insulin glulisine conjugates for insulin delivery
… from commercially available rapid-acting insulin glulisine (Apidra®) and the fluorescent dye FITC (Fluorescein Isothiocyanate) for comparison with the biological activity of native insulin glulisine. The first objective of the study was to produce a single-labelled fluorescent-insulin …
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Synthesis, characterisation and biological activity of FITC-insulin for the development of an artificial pancreas
… kinetics of a synthesisedfluorescently labelled insulin in an implantable artificial pancreas (INsmart device) developed by Tayloret al, 2016, which is currently being tested in-vivo. The first objective of this thesis was to produce a fluorescein isothiocyanate (FITC)-insulin conjugatewhich …
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Investigation into reliability and performance of an implantable closed-loop insulin delivery device
An implantable closed-loop insulin delivery device (INsmart device) containing a glucose responsive gel has been developed within the INsmart research group, over a period of 10 years, to mimic pancreas. In this thesis, the reliability and performance capability of the INsmart device was studied …
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Novel polyelectrolyte complexes for oral insulin delivery.
Oral delivery of insulin used for the management of Type 1 diabetes could be referred to as one of the major long-term goals of diabetes research. However, the bioavailability of orally-administrered insulin is significantly compromised by enzymatic degradation in the GI tract, and poor enteral …