Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"FIP200"”.
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Dissecting the Physiological Roles of ULK1/2 in the Mouse Brain
… mice lacking other autophagy genes (i.e. Atg7 or Fip200), and was associated with abnormal localization of the axon guidance molecule, transient axonal glycoprotein-1 (TAG-1) in the distal CTAs. Approximately 40% of the Ulk1/2 cdko animals died shortly after birth; the remaining animals survived …
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The Non-canonical Function and Regulation of TBK1 in the Cell Cycle
… cells lacking the essential autophagy proteins FIP200 or ATG9A exhibit overactivation and mislocalization of TBK1. By using both genetic and pharmacological inhibition of autophagy processes, we found that impaired autophagy leads to a significantly higher number of micronuclei – a hallmark for …