Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"FGFR3-TACC3"”.
-
Discovery and Elucidation of The Fgfr3-Tacc3 Recurrent Fusion In Glioblastoma
… growth factor receptor 3</em> (<em>FGFR3</em>) gene to the<em> transforming coiled-coil containing protein 3 </em>(<em>TACC3</em>) gene in glioblastoma multiforme. The fusion occurred in 8.3% of patient samples, but not in low grade or normal samples. <em>FGFR3-TACC3 </em>produced an …
-
Development of a Neoepitope Prioritization Platform to Identify Immunogenic Neoantigens from Oncogenic FGFR3-TACC3 Fusion in Glioblastoma
This study investigates the FGFR3-TACC3 fusion as a tumor-specific neoantigen source and establishes an end-to-end computational and experimental framework for the identification, prioritization, and validation of immunogenic neoantigens derived from chimeric RNAs. The FGFR3-TACC3 fusion, generated …