Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"FGF pathway"”.
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Limb cell behaviors in Monodelphis domestica growth and development: the effects of Fgf pathway activators and inhibitors
… (Chapter 1). I then elucidated the role of the Fgf/MAPK signaling pathway in driving these cellular processes (Chapter 2). Results suggest that molecular signals from within the limb drive differences in cell proliferation and focal adhesion that contribute to the differential growth of the …
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Identification and characterization of genetic interactors of the Rho Guanine-nucleotide exchange factor Pebble in <em>Drosophila</em>
… spreading of mesoderm cells is controlled by the FGF signalling pathway acting through the FGF receptor Heartless (Htl). Pbl represents an important downstream component of this FGF pathway and activates the Rho GTPase Rac, but the regulation of Pbl by FGF signalling is unclear. Furthermore Pbl is …
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The Role of Acidic Fibroblast Growth Factor and Fibroblast Growth Factor Receptor 4 In High Grade Serous Carcinoma
… particular acidic fibroblast growth factor (<em>FGF1</em>) has been demonstrated to be one of the driving genes in mediating the observed prognostic effect of the amplicon in ovarian cancer patients. This study seeks to further validate the prognostic value of fibroblast growth receptor 4 …
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A genetic analysis of somitogenesis in the Medaka (Oryzias latipes)
… is regulated by a complex interplay of different pathways. Notch/Delta signaling is one of the pathways well characterized in zebrafish through mutants affected in its different components. Previous work in mouse, chicken and zebrafish has shown that also additional components are required during …