Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"FG-repeats"”.
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Selective transport of the nuclear pore complex studied through all-atom and coarse-grained molecular dynamics simulations
… central pore are many intrinsically unstructured FG-nups, proteins that contain phenylalanine-glycine repeating sequences (FG-repeats) separated by hydrophilic linker regions. Because of the unstructured nature of FG-nups, no imaging method has been able to capture the collective conformation of …
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Understanding biological hydrogel function through design of simplified peptides and polymers
… function, such as the phenylalanine-glycine (FG) repeats in nucleoporin proteins of nuclear pore complexes (NPCs) and the proline-threonine-serine (PTS) domains in mucin polymers found in mucus.
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Discrete 3D Model of Molecular Diffusion Through the Nuclear Pore Complex
… by the dense layers of phenylalanine-glycine (FG) repeats located in the channel and a concentration of transport receptors located on either ends of the NPC. The model simulated the movement of spherical molecules through the NPC and kept track of their location during their transport. The …
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Molecular mechanisms of gating and selectivity in transport channels
… that are rich in phenylaline- glycine motifs (FG-nups) form the central transport channel. Small molecules passively diffuse through the channel but, larger molecules are selectively transported via transport factors (TFs), which apparently interact with the FG-repeats of the nups in the …
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The function of Nup358 in nucleocytoplasmic transport
… Vertrebratenzellen. Einige seiner Merkmale wie FG-Repeats, vier Bindestellen für die GTPase Ran und assoziiertes RanGAP1 könnten direkt mit Kerntransport in Verbindung gebracht werden. Es wurde jedoch nachgewiesen, dass der Transport von Standardkernproteinen auch ohne Nup358 erfolgen kann. Im …
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Structure and Organization of Nuclear Pore Proteins
… structural techniques. These proteins (the FG nups) contain multiple phenylanine-glycine repeats, which bind cargo and transport it through the pore. Although many conflicting models for transport have been proposed, the mechanism still remains unclear. Polarization fluorescence microscopy …