Global ETD Search

FAMIN in dendritic cells biochemically restrains T cell priming

Ramshorn, KatharinaUniversity of Cambridge2022

FAMIN is a purine nucleoside enzyme that was first identified in genome-wide association studies (GWAS) as increasing risk for Crohn’s disease (CD). Defects in the enzyme that result in loss of catalytic activity are the only known monogenic cause of Still’s disease, a severe autoinflammatory …

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FAMIN Functions at the Interface of Purine, Polyamine and Energy Metabolism

Rodrigues, Rodrigo Pereira de AlmeidaUniversity of Cambridge2020

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Characterisation of Mefloquine accumulation in Plasmodium falciparum

Walden, Jason CDivision of Clinical Pharmacology2003

… This adds weight to previously published work (Famin & Ginsburg, 2002) suggesting that chloroquine prevents the degradation of haemoglobin, while mefloquine inhibits the endocytosis of haemoglobin.

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Proteins involved in the pathogenesis of Crohn’s Disease

Bhattacharyya, JoyaUniversity of Cambridge2019

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