Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 45 for “"F410 - Forensic science"”.
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Glioma genetic profiling: The role of DNA repair and telomerase
Brain cancers inflict a disproportional burden of mortality upon sufferers. Due to the difficulties of diagnosis and treatment, survival is low with most patients succumbing to the disease within a year of diagnosis. This has been the imperative factor to underpin some of the molecular mechanisms …
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Exploring role reversal within the victims and perpetrators of domestic abuse
The aim of the research was to explore incidents of Intimate Partner Abuse to develop a deeper understanding of the relationship dynamics between victims and perpetrators of Intimate Partner Abuse (DOMESTIC ABUSE). The study used a quantitative analysis of data obtained by Merseyside Police in May …
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Intimate Partner Violence Victimology: Factors Affecting Victim Engagement with the Police and Criminal Justice System
The thesis concerns an examination of victim engagement with the police investigation of domestic abuse. Notwithstanding the huge efforts being made in tackling the problem by police forces across the UK, national inspections still find that the services provided to victims are “not good enough” …
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A study to investigate the persistence of polydimethylsiloxane and to determine the detection of polydimethylsiloxane in a body fluid matrix following Cellmark’s Sperm Elution©
… sample to allow complete analysis. In current forensic casework, forensic experts don’t usually suggest lubricant analysis if the time that the intimate swabs were taken exceeded 24 hours since the alleged sexual assault. Previous research implied that PDMS was able to be detected in the vagina …
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Methods for Improving Challenging DNA Profiles and Molecular Preservation of Soft Tissue Samples
Degradation of DNA can lead to either poor quality, imbalanced, or even no profiles. Therefore, appropriate collection and storage methods are critical to minimize its impact. If the DNA is degraded prior to sample collection, then the degradation process can only be arrested and other methods have …
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A study on the removal of common analgesics from waste water, using zeolites Clinoptilolite and Beta
Over the last few decades the use of pharmaceuticals has increased to a high level. Used by both humans and animals, pharmaceutical active compounds (PACs) are not completely metabolised inside their bodies. Consequently, PACs are excreted through urine or faeces and together, with the products of …
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The effect of membrane lipid hydrogenation on drug metabolising activity
A range of monometallic Pd-PVP(Poly(2-vinylpyrrolidone) and bimetallic PdRh-PVP catalysts, of different molecular weights were synthesized, for the catalytic hydrogenation of double bonds within the membranes of biological systems. The use of these catalysts would therefore allow investigation as …
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Anticancer a-helical peptides and their structure / function relationships underpinning their interactions with tumour cell membranes
Over the last decade there has been an increase in premature deaths due to cancer. The identification of new chemotherapeutic agents has led to the discovery of toxic peptides with cancer cell specificity. Extensive research is therefore required to determine how these anticancer peptides (ACPs) …
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A spectroscopic study of paint
… commonest forms of trace evidence submitted to a forensic laboratory for analysis. It is essential that techniques are available that allow rapid and confident discrimination between different samples. The aim of this study was to ascertain the discrimination that could be achieved between twenty …
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Evaluation of insertion / deletion polymorphisms (INDELs) applied to forensic casework in Malaysia
In Malaysia, as well as other forensic laboratories in tropical climates many of the crime scene samples received at the forensic laboratory are less than ideal. They are often present low amounts and/or degraded due to environmental exposure to high temperatures, sun and humidity for days or even …
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Confirming the status of Lancashire’s endemic freshwater Nemertean – Prostoma jenningsi
The aim of this study was to confirm the status of Lancashire’s endemic freshwater Nemertean – Prostoma jenningsi. Due to human induced environmental change and the degradation of habitats, a vast decline in biodiversity has been witnessed on a global scale, with losses occurring among many native …
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Analysis of catabolic plasmids in pseudomonas
The experimental work carried out for this thesis concentrated on two separate aspects of the molecular biology of toluenedegradative (Tot) strains of Pseudomonas. Pseudomonas strain Mr74 harbours the single TOt plasmid pWW74, and this plasmid carries two related genes for catechol 2,3-oxygenase …
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Removal of organic pollutants present in water using inorganic-organic Hybrid Multifunctional Nanocomposites
Novel multifunctional nanocomposites were synthesised for the removal of organic dye pollutants from contaminated water samples. Nanocomposites were functionalised to remove dyes via adsorption, photocatalytic breakdown and separation of the nanocomposites from water by simple magnetism. Two types …
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An evaluation of genetic markers for forensic identification of human body fluids
… are commonly recovered from crime scenes by forensic investigators and their identification are necessary part of forensic casework study. Current body fluid identification techniques rely on enzymatic tests, which have limited sensitivity and specificity, they require large amount of …
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An evaluation of analytical techniques, including Raman Spectroscopy, for use in forensic document examination
… encountered in the investigation of crime. Forensic document examiners need to be able to employ techniques that are non-destructive, reliable and admissible in court. In this work, techniques currently in use for ink analysis, including FLE, TLC, UV - Vis, IR-ATR and Raman spectroscopy, …
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Investigation into the structure function relationship of the membrane interaction of amphiphilic alpha helical antimicrobial peptides
Many eukaryotic organisms produce membrane interactive, a-helical antimicrobial peptides (a-AMPs) and a database of such peptides, together with selected physiochemical parameters was established. This database was divided into four groups according to the a-AMPs target organism(s) (active against …
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The application of DNA profiling to the identification of victims in the Gulf war (1990-1991)
This project was designed and developed in response to the need to improve the methodology employed in the DNA profiling of the Kuwaiti victims of the First Gulf War (1990-1991). The main challenges have involved developing the methodology in an attempt to increase the DNA recovery from the …
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Molecular epidemiology of M. Tuberculosis transmission in the United Arab Emirates
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. The people from South East Asian countries constitute the bulk of immigrant resident work force in the United Arab Emirates (UAE) and neighboring Gulf Countries. It is a common believe that TB infected expatriates, are …
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An investigation of CSF dynamics and biochemical composition in normal pressure hydrocephalus utilizing the phase contrast MRI scanning
Normal pressure hydrocephalus (NPH) is a known cause of dementia. It is the only type of dementia which can be treated surgically by pulling a ventriculo-peritoneal shunt to drain excess cerebrospinal fluid (CSF) from the ventricles of the brain. In addition, it is associated with difficulty in …
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Endogenous cardioactive substances in blood: effects on the isolated guinea-pig atria
Investigations were made into the role of blood-borne substances affecting myocardial contractility. Isolated left and right guinea-pig au -ia were used as bioassay for the detection of endogenous cardiotonic substances in bovine serum. Results show that serum that had been buffer exchanged to …
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