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Showing 1 to 8 of 8 for “"F1Fo- ATP Synthase"”.
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Charakterisierung der Untereinheit e der mitochondrialen F1FO-ATP Synthase aus Saccharomyces cerevisiae
… der Untereinheit e (Sue) der mitochondrialen F1FO-ATP Synthase von Saccharomyces cerevisi-ae. Anhand der Resultate der durchgeführten Experimente wurden folgende Schlussfolgerungen gezogen: (1) Sue ist der Lage, ein Sue-Homodimeres zu bilden. Das Protein spielt eine zentrale Rolle bei der …
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Molecular Dynamics Simulations and Cross-Link Analysis of the Rotary Molecular Motor F(o) of ATP Synthase
The protein F1Fo ATP synthase is responsible for the generation of the molecule adenosine tri-phosphate (ATP). It consists of two coupled rotary motors, F1 and Fo. ATP is generated via a rotary mechanism that couples the synthesis of ATP in F1 to the proton translocation across Fo which is driven …
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Paracoccus denitrificans as a model system for studying the mechanism of respiratory complex I
… to the proton motive force used to synthesise ATP. Although structural knowledge of complex I is now extensive, the mechanisms by which it captures the redox energy for proton translocation, and the mechanisms and pathways of the proton pumps, remain elusive. In this thesis, the α- …
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Elucidating the mechanism of mitochondrial superoxide production in pro-inflammatory macrophages
… give rise to these conditions are repurposing of ATP production from oxidative phosphorylation to glycolysis, which reduces the reliance on F1FO-ATP synthase activity resulting in an elevated ∆p, and succinate oxidation which maintains a reduced CoQ pool. Since a high ∆p and reduced CoQ pool could …
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Chlorid, ein neues Signalmolekül für Bakterien
1. Der Aufbau des Membranpotentials und die ATP-Synthese in H. halophilus wurden durch Cl- nicht beeinflußt. Zusammen mit den Ergebnisse früherer Studien gibt es keinen Hinweis darauf, daß Cl- an der primären Bioenergetik von H. halophilus beteiligt ist. 2. Es wurde ein unter Hochsalzbedingungen …
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Requirement of ßDELSEED-Motif of <em>Escherichia coli</em> F<sub>1</sub>F<sub>O</sub> ATP Synthase in Antimicrobial Peptide Binding.
<p>F<sub>1</sub>F<sub>O</sub> ATP synthase is a membrane bound enzyme capable of synthesizing and hydrolyzing ATP. Lately, α-helical cationic peptides such as melittin and melittin related peptide (MRP) were shown to inhibit <em>E. coli</em> ATP synthase. The proposed but unconfirmed site of …
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Inhibition of <em>Escherichia coli</em> ATP Synthase by Polyphenols and Their Derivatives.
… polyphenols on <em>Escherichia coli</em> ATP synthase to test (I) if the beneficial dietary effects of polyphenols are related to their inhibitory actions on ATP synthase, (II) if inhibitory effects of polyphenolic compound could be augmented through structural modifications, and (III) if …
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Molecular Modulation of a-Subunit VISIT-DG Sequence Residue Asp-350 in the Catalytic sites of <em>Escherichia coli</em> ATP Synthase.
<p>ATP Synthase is the fundamental means of cellular energy production in animals, plants, and almost all microorganisms. In order to understand the mechanism of ATP catalysis, critical amino acid residues involved in Pi binding have to be identified. The αVISIT-DG sequence at the interface of α/β …