Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"F protein"”.
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Regulation of the Human Parainfluenza Virus (hPIV3) Fusion Protein
… of this work was to determine how the fusion (F) protein is regulated with a focus on the heptad repeat B (HRB) region of the F protein located in the ectodomain, directly adjacent to the transmembrane domain. This region has been suggested to play important roles in the initiation of fusion</p> …
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Charakterisierung von reptilienpathogenen Paramyxoviren und Analyse des prokaryotisch exprimierten partiellen Fusionsgens
… phylogenetic analysis based on partial L and F protein sequences included the FDLV and the established paramyxovirus type species. In this case, the FDLV showed the closest relationship to the Sendai virus. The fusion (F) gene and protein of the reptilian paramyxovirus isolated from the snake …
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Complexity of the Late Stages of GPI Anchor Biosynthesis in Saccharomyces Cerevisiae
I identified a yeast homolog of the human PIG-F protein, a protein suspected of adding phosphoethanolamine to the third mannose of the mammalian GPI anchor. Genetic disruption of the yeast PIG-F gene (termed GPI11), demonstrated that it is essential for vegetative growth. Yeast gpi11 mutants in …
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Modulation of Immune Responses Induced by Vaccination Against Bovine Respiratory Syncytial Virus
… intranasally-delivered FI-BRSV or BRSV F protein co-formulated with CpG ODN and PP developed higher levels of immunity and protection than mice that received parenterally delivered vaccines. Because of the similarities between BRSV and HRSV, co-formulation of intranasally delivered HRSV …
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Viral and Cell Type Specific Host Factors that Contribute to Paramyxovirus Antiviral Responses
… no defect in growth, in fact the rate of viral protein expression was ~2 fold higher than that seen in WT SV5 infection. Despite expression of a functional viral V protein antagonist, the Le mutant induced IL-6 and IFN-β secretion. Mild CPE involving formation of syncytia was also observed …
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Production of plant-expressed virus-like particle vaccines against infectious bronchitis coronavirus and vaccine efficacy in chickens
… produced using Agrobacteriummediated transient protein expression in Nicotiana benthamiana plants as potential vaccines against IBV. Modifying the full-length IBV Spike (S) protein resulted in high levels of VLPs resembling native IBV particles visualised under transmission electron microscopy. …
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Untersuchung der Masernvirus-induzierten Immunsuppression im Baumwollrattenmodell
… zeigte, dass Impfstämme, welche das Oberflächenprotein H von WTF anstelle des H-Proteins von Edm tragen, proliferationshemmend sind und sich im Organismus ausbreiten. Das F-Protein von Edm oder WTF hatte keinen Einfluß auf Immunsuppression und Virusausbreitung, Die Rückmutation in dem WTF …
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Differential proteomic profiling towards elucidation of TB-IRIS pathogenesis
… immunometabolic functional specialisations. Proteins represent the most functionally-proximal and commonly pharmacologically-targeted cellular biomolecules. Label-free high-performance liquid chromatography-coupled tandem mass spectrometry (HPLCMS/MS) is well-suited to differentially …
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Exploring the emergence of pesticide degradation in the α/β hydrolase superfamily
… provides a dynamic testing ground to observe protein evolution in fast-forward mode. In this global experiment, we can observe the emergence of new enzymatic activities and compare the adaptability of different catalytic motifs. Among the xenobiotic substances used, phosphotriester pesticides …