Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 30 for “"Eye disease"”.
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Key informants for peadiatric eye disease case finding in Madagascar
… between 2 -8 per 10,000 children. Childhood eye disease is rare and conditions are difficult to detect; thus, surveys to estimate the prevalence of blindness requires rigorous, costly and difficult methods to obtain reasonable estimates among children. Key informant programs, which engage the …
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The psychosocial and clinical outcomes of surgery for Thyroid Eye Disease (TED)
… whether quality of life in patients with thyroid eye disease (TED) improves as a result of having orbital decompression surgery and whether any demographic, clinical or psychosocial factors can predict which patients might benefit from this surgery. One hundred and twenty three adults with TED …
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Evaluating the Role of the Ocular Surface Microbiome in Dry Eye Disease Mediated Neural Dysregulation
Dry eye disease (DED) is a multifactorial ocular surface disorder arising from a loss of homeostasis at the corneal-tear interface. This leads to visual and neurosensory abnormalities which are regulated by the corneal-trigeminal ganglion pathway. An important contributor to ocular homeostasis is …
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Exploring Routine Sight Testing And The Management Of Eye Disease By Primary Care Optometrists In England, UK
… (9%). The study examining the need for a Minor Eye Condition Service in Leeds and Bradford found it would produce theoretical cost savings, whilst maintaining high patient satisfaction. Subsequently, a MECS was commissioned in Bradford. The study attempting to collect data from MECS across all …
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Visual functioning and quality of life after pars plana vitrectomy for diabetic eye disease at Groote Schuur Hospital, Cape Town, South Africa
… age, gender, the presence systemic disease and best-corrected visual acuity (BCVA).
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Smart Ocular Implant for Monitoring IOP in Glaucoma Patients
… the ’thief of sight’ or the ’silent blinding eye disease’. As the world’s second most blinding eye disease and the number one irreversible eye disease, numerous studies have shown that pathological IOP is a significant risk factor. A single clinical examination of vision cannot detect an …
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Avaliação da superfície ocular em pacientes com doença ocular da tireoide
Introduction: Thyroid eye disease (TED) is the most common and severe extrathyroidal manifestation in patients with Graves' disease, affecting 25-50% of these patients. Ocular surface disease (OSD) is a multifactorial disorder characterised by an imbalance in tear film homeostasis, resulting from …
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Relevance and Role of Nutritional Supplements in the Ophthalmology Practice // Място и роля на хранителните добавки в офталмологичната практика
… (POAG) is a chronic, progressive, irreversible eye disease that potentially leads to blindness, causing damage to the optic disc and neurofibrillary layer, with associated visual field defects. All available therapeutic strategies are currently limited to lowering IOP, which has been shown to …
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Pathogenesis of Dry Eye in Graft Versus Host Disease (GVHD): Role of Ocular Mucins and Conjunctival Fibrosis
… major side effect i.e Graft vs. Host Disease (GVHD). GVHD is a complex, multi-organ disease resulting from an immunological attack by donor engrafted immune cells to host organs, including the eye surface. Mostly based on the time of disease onset after transplantation, GVHD is divided …
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Folding, stability and aggregation of the long-lived eye lens protein human gamma D crystallin
… found in high concentrations in the human eye lens. H[gamma]D-Crys and other crystallins are found in insoluble protein inclusions associated with the eye disease cataract. H[gamma]D-Crys is expressed in utero and does not regenerate during life, thus necessitating high stability and …
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Ophthalmological Perspectives On Children's Eye Health // Офталмологични перспективи на детското очно здраве
… for ensuring positive perspectives on children's eye health. Methods: Information was utilised from primary outpatient ophthalmological examinations of children (0-17 years) for the period 2019-2022, extracting data on the examination date, age, and gender of the patient, and primary diagnosis. …
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ANALYSIS OF MICROBIOME IN VARIOUS HUMAN MEDICAL CONDITIONS USING NEXT-GENERATION SEQUENCING OF THE 16S rRNA GENE
… within the body. Influenced by age, gender, and disease, it mirrors broader microbial ecosystems. This study specifically delves into the ocular and gastrointestinal tract microbiome, comparing its composition in 43 healthy and diseased patients using 16S rRNA gene sequencing. We identified a …
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Exploring public health intervention strategies to address barriers and challenges in the prevention of avoidable blindness due to glaucoma in Anambra State, Nigeria
… the need for countries to address the issue of eye health with increased effort. However, due to scarcity of both human and material resources in Nigeria and many other developing countries health care is often marginalised; especially eye health. This contributes to the rise in prevalence of …
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The Transformation of Human Retinal Pigment Epithelial Cells
… vitreoretinopathy (PVR) is a fibrotic eye disease and the most common cause of fail ure of retinal reattachment surgery. Although the etiology of this disease is unknown, TGFβ has been implicated as a key factor contributing to PVR.</p> <p>The risk factors of PVR include a tear on the …
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The Association of Arterial Stiffness with Diabetes and Microvascular Disease
… is a risk factor for diabetes and microvascular disease, and if so, whether aortic PWV estimated with a single cuff oscillometric device PWV (oPWV), which is easy-to-apply in clinical practice, can predict future disease incidence. Methods Four systematic reviews were conducted based on existing …
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Mechanism of the efficient quenching of tryptophan fluorescence in human gamma crystallin
… (H[gamma]S-Crys) are both very stable eye lens protein that must remain soluble and folded throughout the human lifetime. Aggregation of non-native or covalently damaged H[gamma]D-Crys or H[gamma]S-Crys is associated with the prevalent eye disease mature-onset cataract. Both …
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Structural and functional characteristics of meibomian glands in meibomian gland dysfunction
… contact lens wearers and participants with dry eye disease (DED). The third prospective study used multimodal imaging to evaluate MG orifices and explore their associations with, and ability to predict symptoms. The fourth study investigated inter-day and intersubject variations in meibum lipid …
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Reiterative FGF signaling determines the identity and morphology of the lacrimal gland
… in the lacrimal gland is the main cause of dry eye disease, but existing treatments only alleviate the symptoms without curing the underlying disease. To develop curative measures, a thorough understanding of lacrimal gland development is needed. Lacrimal gland is formed as a result of …
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Imaging of Meibomian Glands in Various Species
… for tear stability which is disrupted during dry eye disease. Blink rate varies across species suggesting differences in tear film stability, MG anatomy, and meibum quality. Meibography is performed on humans, but little is known about MG in other species. Using ex vivo meibography we imaged and …
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Characterization of Ocular Surface Pathology and Tear Film Dysfunction Due to Type 1 and Type 2 Diabetes Mellitus
… affecting heart, nerves, kidney, and eyes. While the etiological mechanisms of diabetes-associated retinopathy and cataract have been well characterized, the time kinetics and the severity of diabetes-mediated injury to the ocular surface and its various components like tear film, …
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