Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 31 for “"Eye Diseases"”.
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Long Term Ocular Drug Delivery with Novel Pentablock Copolymers; Part I: Composite Nanoformulation of Macromolecules For Back of the Eye Diseases, Part II: Dexamethasone Nanoparticle to Develop an In Vitro Model for Glaucoma
… in the treatment of posterior segment ocular diseases. PB copolymers are comprised of FDA approved biodegradable polymer such as polyethylene glycol (PEG), polycaprolactone (PCL), polylactic acid (PLA) and polyglycolic acid (PGA). PB copolymers of different composition, molecular weights and …
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Ophthalmological Perspectives On Children's Eye Health // Офталмологични перспективи на детското очно здраве
… for ensuring positive perspectives on children's eye health. Methods: Information was utilised from primary outpatient ophthalmological examinations of children (0-17 years) for the period 2019-2022, extracting data on the examination date, age, and gender of the patient, and primary diagnosis. …
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Therapeutic effects of N-acetylcysteine amide in the treatment of eye disorders
<p>"The loss of vision from age-related eye diseases now affects over 30 million people in the United States and is expected to reach twice that number within the next couple of decades. Among these disorders, age-related macular degeneration and cataract formation represent the largest percentage …
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Topical Nanoparticulate Formulation of Drugs for Ocular Keratitis
… delivery system for the treatment of anterior eye diseases. Maximum uptake (around 60%) was noted at 3 h for NP. Cellular uptake and intracellular accumulation of prodrugs are significantly different among three stereoisomeric dipeptide prodrugs. The microscopic images show that NP are avidly …
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FGF signaling in Xenopus laevis lens regeneration
… work may guide subsequent research in treating eye diseases.
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A morphological study of an eye anomaly in the albino rat
Thesis (M.S.)--Michigan State College of Agriculture and Applied Science. Dept. of Zoology, 1948
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Evaluation of the visual pathway with ERG, mfERG and mfVEP in inherited eye disorders
… in patients with different hereditary eye diseases and to further evaluate and modify the mfVEP technique for clinical use. Bothnia Dystrophy is a tapetoretinal disorder with a mutation in the RLBP1 gene. Early in the disease the fundus may have a normal appearance. The full-field ERG …
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Photosensitizer Loaded Contact Lenses As An Externally Stimulated Ophthalmic Drug Delivery System
… associated with the treatment of ocular diseases. 90% of the ophthalmic dosage forms are given topically. However, following the topical route, only 5% ocular bioavailability is achieved. The aim of my work is to address the problems associated with the conventional topical application. …
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TWEAK/Fn14 Pathway is Activated by Hypoxia and is a Novel Mediator of Retinal Neovascularization
… (NV) is a major cause of vision loss in vascular eye diseases such as diabetic retinopathy, retinal vein occlusion and retinopathy of permaturity. Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) and its receptor, fibroblast growth factor inducible 14 (Fn14), have been implicated …
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Benefits and accessibility of OCTA imaging for diabetic retinopathy and macular edema
… retinal microvascular changes in diabetic eye diseases. This study aims to evaluate the cost-effectiveness of different screening strategies incorporating OCTA for the detection and management of DR and DME. A decision tree model (Figure 2) was created to estimate the cost consequences of …
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In vitro corneal ion and water movement in the rainbow trout, Salmo gairdneri
Thesis (M.S.)--Michigan State University. Dept. of Physiology, 1964
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Investigating quality of life in inherited optic neuropathies: Evaluating patient experiences and outcome measures
… optic neuropathies (IONs) are a group of rare eye diseases characterised by bilateral and progressive degeneration of the optic nerve due to mitochondrial dysfunction. The two most common IONs encountered in clinical practice are autosomal dominant optic atrophy (DOA) and Leber hereditary optic …
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Ocular Iontophoresis of Nanocarriers for Sustained Drug Delivery to the Eye
… deliver therapeutic drugs for the treatment of eye diseases. Although several studies have been conducted to examine the utility of iontophoresis for both charged and neutral molecules, the understanding of the mechanisms controlling the iontophoretic delivery of macromolecules across human …
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TOLL-LIKE RECEPTOR EXPRESSION AND FUNCTION
… presents from various etiologies (e.g. dry eye and Pseudomonas aeruginosa (PA) infection), yet little is known about the role of toll-like receptors (TLR) which, upon activation, stimulate inflammation. The objective of this research was to determine: (1) baseline expression of TLRs in …
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Detection and Classification of Diabetic Retinopathy Pathologies in Fundus Images
… of the disease. Accurate, early detection of eye disease is important because of its potential to reduce rates of blindness worldwide. Retinal photography for DR has been promoted for decades for its utility in both disease screening and clinical research studies. In recent years, several …
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Nanomicelles And Liposomes For Improving Drug Delivery of Small Molecules And siRNA Therapeutic Agents
… TACROLIMUS NANOMICELLES FOR BACK OF THE EYE DISEASES Vrinda Gote, Candidate for the Doctor of Philosophy Degree University of Missouri-Kansas City, 2021 ABSTRACT Neovascular age-related macular degeneration (AMD) is characterized by increase in reactive oxygen species (ROS) and …
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Exploring public health intervention strategies to address barriers and challenges in the prevention of avoidable blindness due to glaucoma in Anambra State, Nigeria
… the need for countries to address the issue of eye health with increased effort. However, due to scarcity of both human and material resources in Nigeria and many other developing countries health care is often marginalised; especially eye health. This contributes to the rise in prevalence of …
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Hereditary progressive arthro-opthalmopathy (Stickler Syndrome): a clinical analysis and search for linkage
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Pathogenesis of Dry Eye in Graft Versus Host Disease (GVHD): Role of Ocular Mucins and Conjunctival Fibrosis
… immune cells to host organs, including the eye surface. Mostly based on the time of disease onset after transplantation, GVHD is divided into the acute and chronic phase. The eyes may be involved in both acute and chronic GVHD, although ocular involvement is more common in the chronic GVHD …
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