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Showing 1 to 11 of 11 for “"Extravillous trophoblast"”.

  1. The role of thyroid hormones in placental development and the importance of the thyroid hormone transporter MCT8

    Vasilopoulou, ElisavetUniversity of Birmingham2010

    … apoptosis of IUGR compared with normal cytotrophoblasts, which was associated with increased MCT8 expression. In normal cytotrophoblasts, MCT8 upregulation decreased survival, whilst MCT8 silencing increased survival independently of T\(_3\). In the extravillous trophoblast-like cell line, …

    birmingham Repository record

  2. TISSUE ARCHITECTURE AND INTERCELLULAR COMMUNICATION: MEDIATORS OF PROTECTIVE OR PATHOGENIC INTERFERON RESPONSES

    Negatu, Seble, Getenet2024

    … relevant functions, such as migration of fetal extravillous trophoblasts into the maternal uterus during implantation. In both models, there are a diverse range of cell types that can contribute to immune responses. Using these models allowed for intercellular communication, and thus advanced …

    penn Repository record

  3. The expression of Heat Shock Protein 70 in the placental tissue with preeclampsia

    김, 호연2011

    OBJECTIVE: Placental ischemia caused by abnormal trophoblastic invasion to spiral arteries, immunologic intolerance and inflammatory change explain etiology of preeclampsia. As a consequence, inflammatory cells are released and they induce oxidative stress contributing to endothelial dysfunction …

    ajou Repository record

  4. The Role of MicroRNA-378a-5p and its Target Genes in Differentiation and Fusion of BeWo Cells

    Nadeem, Uzma2018

    … and formed from the fusion of mononucleated cytotrophoblast (CTBs), syncytiotrophoblasts (STBs) are the primary site of numerous placental functions such as exchange of respiratory gases and waste products, transport of nutrients and hormones production. We have previously shown that miR-378a-5p …

    york Repository record

  5. Physical Factors Regulating Human Trophoblast Invasion

    Abbas, Yassen RaadUniversity of Cambridge2018

    … characterised by inadequate invasion of extravillous trophoblast (EVT) cells into the uterine decidua. This invasion is necessary to transform the uterine arteries, ensuring an adequate maternal blood supply into the intervillous space for normal fetal growth and development. The …

    cambridge Repository record

  6. Die differentielle Expression tumorfördernder und tumorinhibierender Gene im ersten und zweiten Trimester der Schwangerschaft

    Tipp, Alexander JohannesPublikationsserver der RWTH Aachen University2010

    The invasion of the Extravillous Trophoblast (EVT) in human hemochorial placentation is a crucial step in successful pregnancy. Fetal cells invade decidual tissue (the transformed endometrium) and the first third of the myometrium (interstitial invasion) as well as uterine vessels (endovascular …

    aachen Repository record

  7. Trophoblast specification and differentiation potential in early human and non-human primate embryogenesis

    Siriwardena, DylanUniversity of Cambridge2022

    Implantation is mediated by trophoblast, the outer layer of the early embryo. Trophoblast is an extraembryonic tissue that gives rise to the placenta, which sustains fetal growth and development. Human embryo implantation and early trophoblast development have remained elusive due to the …

    cambridge Repository record

  8. Innate Lymphoid Cell Diversity in Pregnancy and Ovarian Cancer

    Huhn, OisinUniversity of Cambridge2019

    … receptors for HLA class I found on invading extravillous trophoblast (EVT) including Killer-cell Ig-like receptors (KIR), LILRB1 and NKG2A. In contrast to dNK2 and dNK3, dNK1 respond poorly to ‘missing self’ and PMA plus ionomycin treatment. However, upon cross-linking of an activating KIR …

    cambridge Repository record

  9. Die Expression der G-Protein gekoppelten Rezeptoren LGR 4, LGR 5, LGR 7 und LGR 8 im humanen nicht-graviden und graviden Uterus sowie in Karzinomzelllinien des Reproduktionstraktes und der Mamma

    Kroll, TinaPublikationsserver der RWTH Aachen University2010

    … several leukocytes and individual cells of the extravillous trophoblast were positive for LGR 7 immunostaining. A specific LGR 8 mRNA expression was detected in myometrium, decidua and placenta. LGR 4 -/- knock-out mice suffer from infertility, indicating that this receptor system plays a role …

    aachen Repository record

  10. Trophoblast Retrieval And Isolation From The Cervix (tric) For Non-Invasive Prenatal Genetic Diagnosis And Prediction Of Abnormal Pregnancy Outcome

    Fritz, Rani2015

    … the first and second trimesters of pregnancy, extravillous trophoblast (EVT) cells invade the uterus and remodel the maternal spiral arteries, which, if inadequate, leads to pregnancy complications, including early pregnancy loss (EPL), preeclampsia (PE), and intra-uterine growth restriction …

    wayne-thes Repository record

  11. Impaired Wnt5a signaling in extravillous trophoblasts: Relevance to poor placentation in early gestation and subsequent preeclampsia

    Ujita, MariKyoto University2019

    kyoto Repository record