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Showing 1 to 1 of 1 for “"Extravasation-rate limited Gewebemodelle"”.
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Modeling approaches to characterize the disposition of monoclonal antibodies
… modeling of mAbs disposition: We demonstrate that binding to FcRn is indeed linear and that it is not possible to infer which tissues are involved in the unspecific elimination of wild-type mAbs. We also provide a new approach to predict tissue partition coefficients based on mechanistic …