Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Extrahepatic delivery"”.
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Engineering Lipid Nanoparticle-Mediated Delivery of Nucleic Acids to Lymphoid Organs and Immune Cells
… are needed for the protection and effective delivery of nucleic acids. Lipid nanoparticles (LNPs) are an established essential platform for nucleic acid delivery. Efforts have led to the development of vaccines that protect against SARS-CoV-2 infection using LNPs to deliver mRNA coding for …
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Design and synthesis of ionisable amino-polyester lipid nanoparticles for extrahepatic RNA delivery
… origins. Advances in mRNA chemistry and delivery technologies have enabled applications ranging from vaccines and cancer immunotherapy to protein replacement and regenerative medicine. Polymeric nanoparticles offer a promising route for extrahepatic mRNA delivery, although challenges such …