Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Extracellular Matrix Remodelling"”.
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The role of extracellular matrix remodelling in brown adipose tissue functions: New candidates
… by the status and functionality of the extracellular matrix (ECM). However, the main obstacle is that obese and diabetic patients have less active BAT mass. Understanding the mechanisms that regulate and impair BAT activity in obesity is essential for developing an efficient strategy to …
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STUDY OF THE EFFECT OF TUMOUR EDUCATED MACROPHAGES ON NEURAL CELLS
… set of properties, including immune suppression, extracellular matrix remodelling, and neoangiogenesis, that, while detrimental in cancer, could be harnessed for promoting tissue regeneration following neurotrauma. Moreover, studies conducted in our laboratory further identified that TAMs are …
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Modulation of Inflammation Driven Wound Healing after Glaucoma Surgery
… NSAID exposure resulted in more ordered extracellular matrix remodelling, less cell-mediated collagen contraction and greater impairment of myofibroblast associated protein expression. We hypothesized that these differences were due to NSAIDs more specific targeting of COX enzyme …
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In Vitro Remodeling of Extracellular Matrix Following Mild Traumatic Brain Injury
… the intricate mechanical interplay between the extracellular matrix (ECM) and astrocytes following a simulated mTBI. Cellular mechanisms underlying mTBI and the contribution of mechanical forces that result in prolonged brain damage are yet to be comprehensively understood. Successfully devised …
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Engineering hiPSCs to enhance neural progenitor transplantation in degenerative cervical myelopathy
… Importantly, the extent of astrogliosis and extracellular matrix remodelling that could limit or enhance neural progenitor cell (NPC) graft efficacy in DCM is unknown. The first aim of this project was to examine changes in the extracellular matrix in DCM. Immunohistochemistry of post-mortem …
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Angiogenesis and angioregression gene expression analyses in swine corpus luteum
… vascular invasion and apoptosis process, the remodelling of the extracellular matrix is essential for the correct evolution of the CL, particularly by the action of specific class of proteolytic enzymes known as matrix metalloproteinases (MMPs). Another important factor that plays a role in …
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Genomic and metabolomic interrogation of body composition and insulin resistance endotypes
… and FMI. The strongest signals highlighted an extracellular matrix/remodelling theme (including multiple ADAMTS/ADAMTS-like family genes), alongside exemplars with mechanistically informative profiles such as ATP2A1 (lean-mass-aligned with supporting biochemical associations) and GH1 …