Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Exon junction complex"”.
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Fission Yeast Exon Junction Complex Orthologs Ensure the Maturation of Meiotic Transcripts During Meiosis
… meiotic genes, Mmi1-NURS (Mtl1-Red1 core) complex shuttles premature meiotic RNAs to be degraded by the 3’-5’exoribonuclease activity of the nuclear exosome. However, its role for meiotic gene expression in meiosis has not been explored. Here, we report that Red5, an essential NURS subunit, …
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Isolation and characterization of Hupf1-containing protein complexes and their role in nonsense-mediated mRNA decay
… for NMD in mammals, Hupf1-containing protein complexes were affinity purified from HeLa cells that stably express recombinant, double affinity tagged Hupf1-2tag at physiological levels. The analysis of these purified complexes by mass spectrometry revealed the presence of the proteins Hupf2 …
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Characterization of nonsense mediated mRNA decay in Schizosaccharomyces pombe
… positioned upstream of at least one intron. The exon junction complex (EJC) is believed to mediate the link between splicing and NMD. However, recent studies have questioned the importance of splicing and the EJC in NMD and instead they have proposed that, from yeast to mammalian cells, NMD is …