Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 32 for “"Exhaled nitric oxide"”.
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Exhaled nitric oxide in asthmatic airway inflammation
Measuring the level of exhaled NO (eNO) in the breath is a new method to monitor airway inflammation in asthma and may have a role in the management of asthma. The hypotheses were that eNO will reflect the degree of inflammation in chronic asthma, and will indicate how anti- inflammatory therapy …
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Non-invasive method of measuring airway inflammation : exhaled nitric oxide
Background Nitric oxide (NO) was well known to be a component of air pollution, often in the form of nitrogen dioxide (NO2). However its importance in biological systems altered dramatically with the discovery in 1987 that it was the 'endothelial-derived relaxing factor'. Since then there has been …
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Determinants of Fractional exhaled Nitric Oxide (FeNO) levels in occupational asthma in different occupational settings
Background: Fractional exhaled nitric oxide (FeNO) offers a potential tool for screening and surveillance of workers at risk of occupational respiratory allergy and asthma. Objective: This study evaluated determinants of FeNO in workers at risk of occupational respiratory allergy and asthma in …
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Assessing the health impact of intervention in supermarket bakeries using fractional exhaled nitric oxide (FeNO) and other clinical endpoints for baker’s allergy and asthma
… in supermarket bakeries using fractional exhaled nitric oxide and other clinical endpoints for baker’s allergy and asthma after a one-year follow-up period. Methods: A field randomised controlled trial of 31 bakeries initially assigned to one of two intervention groups (bakery mixer lid …
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The relationship between pesticide metabolites and asthma outcomes among women farm workers
… airway inflammation as determined by fractional exhaled nitric oxide (FeNO) and low levels of whole blood cholinesterase among women farm workers. The main objective of this study was to investigate the relationship between exposure to different pesticides (ascertained through pesticide …
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Reduced corticosteroid sensitivity in smokers with asthma: potential mechanisms and treatment
… response displayed by smokers with asthma. Exhaled nitric oxide has been exploited as a useful exploratory and confirmatory endpoint in asthma. However exhaled nitric oxide, measured using standard flow rates and methodology, is unhelpful in smokers with asthma as cigarette smoking is …
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From sneeze to wheeze: Non-invasive studies on asthma and rhinitis
… non-invasive techniques such as induced sputum, exhaled nitric oxide and impulse oscillometry in addition to bronchial provocation tests we found signs indicating a higher degree of peripheral airway involvement in the asthmatic group. The transition from allergic rhinitis to clinical asthma is …
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Respiratory allergy and asthma associated with pesticide exposure amongst women in rural Western Cape
… Respiratory Health questionnaire, fractional exhaled nitric oxide (FeNO) levels and immunological tests (a positive Phadiatop test indicating atopy and quantification of specific IgE to house dust mite, storage mite and spider mite). The outcome variables included doctor diagnosed asthma, …
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Exhaled breath analysis using laser absorption spectroscopy
… techniques were employed to measure exhaled nitric oxide (NO), carbonyl sulfide (OCS) and carbon dioxide (CO2). A pulsed quantum cascade laser operating at 4.86 microns was coupled to a 36-m optical path length Herriott cell for simultaneous measurement of exhaled OCS and CO2. Exhaled …
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Modification by sex and atopy of the effect of chemical air pollutions and biological air pollutants including pollen and fungal spores on children respiratory health in the Western Cape, Cape South Africa
… questionnaire, spirometry, and fractional exhaled nitric oxide (FeNO) testing. The study found that increased annual grass pollen levels and annual NO2 levels were positively associated with airway obstruction (OR: 2.26, 95% CI: 1.02-5.03) for annual grass pollen and FeNO (OR: 2.43, 95% …
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Determination of endogenous and dietary-derived nitric oxide production in exhaled air of adult humans
The production of nitric oxide (NO) has been demonstrated in the human body. Studies have elucidated that NO can either be produced endogenously via enzymatic action or through exogenous factors from dietary nitrate reduction. Exhaled nitric oxide (eNO) levels were also observed to be increased in …
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The relationship between urinary organophosphate pesticide metabolites and asthma-related outcomes at 12-month follow-up in school children residing in informal settlements in the Western Cape
… characteristics. Spirometry and fractional-exhaled nitric oxide (FeNO), including a phadiatop test (atopy status) and urinary dialkyl phosphate (DAP) metabolites diethylphosphate (DEP), dimethylthiophosphate (DMTP)] were measured at baseline and follow-up. Dimethylphosphate (DMP) was …
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The effect of Vitamin D status on lung function and airway inflammation in adults in Saudi Arabia and the UK
… 0.287; FVC, P 0.391), slightly lower fractional exhaled nitric oxide levels (P 0.719) and lower blood inflammatory biomarkers, however, did not reach significant levels. Healthy participants with higher vitamin D levels had also better lung function (FEV1, P 0.104, FVC, P 0.158) but no …
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The study of occupational risk factors and interventions for baker's allergy and asthma among supermarket bakery workers
… methacholine challenge test and fractional exhaled nitric oxide (FeNO). Exposure assessment conducted pre- and post-intervention entailed determination of inhalable concentration of particulate mass and specific allergen levels. The intervention employed a group-randomised design to evaluate …
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Allergen-induced change in airway responsiveness to direct and indirect stimuli in mild atopic asthmatics
… challenges were separated by 14 days. Fractional exhaled nitric oxide measurements (FENO) were collected in both studies at varying time points to track airway inflammation. In the 3-hour study, the geometric mean MCh PC20 decreased significantly after allergen exposure from 0.88 mg/ml to 0.50 …
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Allergic sensitization and work related asthma among poultry workers in South Africa
… ECRHS questionnaire, spirometry, fractional exhaled nitric oxide, Phadiatop and ImmunoCAP for specific IgE to poultry farming associated allergens (chicken meat, feathers, serum protein, droppings, sunflower seeds, storage mite) and mould mix to investigate workrelated asthma. Results: The …
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Effect of atorvastatin on asthma control and airway inflammation: a randomised controlled trial
… to methacholine (PC20) and inflammatory markers: exhaled nitric oxide, sputum differential cell count, sputum supernatant and serum inflammatory markers such as interleukin-6 (IL-6), IL-5, IL-8, sICAM-1, TNF-α, leukotriene B4 (LTB4) and high sensitivity C-reactive protein (hsCRP), and blood …
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Allergic bronchopulmonary aspergillosis in cystic fibrosis: prevalence, clinical complications, diagnosis and influence on the outcome
… sensitisation. The cross sectional study on exhaled nitric oxide (NO) level shows a significantly decreased level of exhaled NO in patients with high risk of developing ABPA. The prospective study reveals a specific pattern of specific IgG and subclass antibodies to water soluble somatic …
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The effect of domestic mechanical heat recovery ventilation on asthma control of patients allergic to the house dust mite
… but not at 12 months. There was no difference in exhaled nitric oxide, a measure of airway inflammation, between the two groups at 12 months. However, these clinical improvements could not be explained by reduced allergen exposure, as although indoor air humidity was reduced during the winter …
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Exposure to Phthalate Mixtures and Inner-City Pediatric Allergic Disease and Airway Inflammation
… were both associated with higher fractional exhaled nitric oxide, a marker of airway inflammation. These findings suggest several important sources of exposure to phthalates and demonstrate new methods for highly correlated exposures that have not been widely applied in the environmental …
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